Inflammatory Bowel Disease Clinical Trial
— MICIOfficial title:
Inflammatory Bowel Disease : Could a Regular Physical Activity Reduce Patients Fatigue ?
The chronic fatigue is observed in approximately 40 % of the patients with a chronic quiet
inflammatory bowel disease (IBD) and impacts the quality of life of the patients. The
beneficial role of a regular physical activity on the quality of life of patients having an
IBD was demonstrated in 5 studies including only 1 controlled one [Bilski, on 2013]. The
mechanism by which the physical activity could improve the quality of life of the patients
remains unknown (stress decreased, reduction of the inflammatory process) [Bilski, on 2014].
Several studies concerning other chronic pathologies such as fibromyalgia, have demonstrated
the beneficial effect of a regular physical exercise to reduce the fatigue of patients. It
was recently demonstrated that the chronic fatigue observed in patients with IBD came along
with a physical reduction in the performances during the exercise test and a reduction in the
physical activity of the patients [Vogelaar, 2015].
Our hypothesis is that a regular moderate physical activity could improve physical
performance during an effort et could reduce the chronic fatigue and improve their quality of
life.
Status | Recruiting |
Enrollment | 10 |
Est. completion date | April 2018 |
Est. primary completion date | April 2018 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years to 45 Years |
Eligibility |
Inclusion Criteria: - Patients = 18 years old - Patients suffering from IBD - Patients with a FACIT score < 30 - Patients with BD in remission with a C-reactiv protein dose < 5 - Patients with Hemoglobin dosage > 10g/dl - Patients with 18<BMI<30 kg/m2 - Informed consent given by the patients - Patients affiliated to the social security - Patients living not far from the centre where the rehabilitation program will be performed - Women with no risk of pregnancy (menopausal women or with contraceptive drugs). Exclusion Criteria: - Patients = 45 years old - Inability to walk or to ride a bike - Contraindication to practice physical exercise - Contraindication to exercise test - Participation to another research study within the week preceding the beginning of the protocol - Patients unstable smokers - Patients unable to keep their medical treatment stable along the study - Patients with a regular intensive physical practice - Patients with depression (HAD>11/21) - Patients with bad sleep quality (PSQI score >5) - Pregnant or breast-feeding patients - Patients under legal protection |
Country | Name | City | State |
---|---|---|---|
France | Rouen University Hospital | Rouen |
Lead Sponsor | Collaborator |
---|---|
University Hospital, Rouen |
France,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Difference from baseline in the evaluation of fatigue | Evaluation of fatigue using FACIT questionnaire | 3 Month | |
Secondary | Difference from baseline in the Evaluation of the Quality of life | Evaluation of the Quality of life using Quality of life scores (IBDQ) | 3 Month | |
Secondary | Difference from baseline in the Evaluation of the Quality of life | Evaluation of the Quality of life using Quality of life scores (SF36) | 3 Month |
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