Effect of Dexamethasone on Postoperative Inflammatory Factors

Status Recruiting

Clinical Trial Summary

This topic foe randomized prospective study.Detection of elderly patients with lunmbar spinal postoperative inflammatory substances in the blood and drainage of liquid level ,clear whether low-dose dexamethasone can inhibit the inflammation, the observation of elderly patients with lumbar spinal postoperative drainage star, to explor whether low-dose dexamthasone can reduce postoperative incision drainage, thus impove the postoprative drainage tube pull rate within three days, which in turn reduce because of the place a retrograde infection caused by drainage tube.

Clinical Trial Description

A total of 100 patients undergoing posterior lumbar disc fusion were randomly divided into control group (group C,n=50) and dexamethasone group (group D,n=50). Group D was given 0.15mg/kg dexamethasone (2ml) intravenously after anesthesia induction. Group C was also intravenously injected with 2ml normal saline after anesthesia induction.On this basis, monitor the main results and secondary results ;

Study Design

Related Conditions & MeSH terms

Inflammation

Clinical Trial Details

NCT number	NCT04981093
Study type	Interventional
Source	General Hospital of Ningxia Medical University
Contact
Status	Recruiting
Phase	N/A
Start date	August 15, 2021
Completion date	June 1, 2023

View Details

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