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Amino Acid Nutrition in the Critically-ill — AA-ICU  

Inflammation Clinical Trial

Official title:
Enhancing the Anabolic Effect of Nutrition in Critically Ill Patients by Administering Exogenous Amino Acids

Clinical Trial Summary

Enhancing the anabolic effect of nutrition in critically ill patients by administering exogenous amino acids.

Clinical Trial Description

Critically-ill patients admitted to the intensive care unit are invariably catabolic and are commonly undernourished. Previous observational studies indicate that increased dietary administration of protein or essential amino acids might be associated with improved clinical outcomes. The investigators propose that the parenteral supplementation of intravenous amino acids in critically-ill patients will restore anabolic processes and that anabolism is associated with molecular markers of amino acid sensing and protein synthesis. The results from this study will establish biomarkers of anabolism (i.e., nutritional success) that can be used in future clinical trials on the use of amino acid supplementation in the critically-ill. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02865408
Study type Interventional
Source McGill University Health Centre/Research Institute of the McGill University Health Centre
Contact Arnold S Kristof, MDCM, FRCPC
Phone 501-934-1934
Email arnold.kristof@mcgill.ca
Status Recruiting
Phase N/A
Start date March 1, 2017
Completion date February 28, 2025
View Details
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