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NCT02692118 Clinical Trial

Inflammatory Mediators in Early Sepsis

Inflammation Clinical Trial

— Tusep  

Official title:
Inflammatory Mediators in Sepsis as Indicator for Infection vs Inflammation

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT02692118
Other study ID # AnaTubingen
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date December 2016
Est. completion date September 2022

Study information
Verified date June 2021
Source University Hospital Tuebingen
Contact Peter Rosenberger, MD
Phone +49(0)7071298
Email peter.rosenberger@med.uni-tuebingen.de
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Sepsis is still a challenge for clinicians since the detailed pathomechanism are still unknown and until now early markers for sepsis are not defined yet. Immunological pathways and new mediators defined in animal models are not yet investigated in patients with sepsis. Therefore the investigators will measure new mediators in patients with septic shock.

Description:

Semaphorins 1 to 7 will be determined in Blood of patients with early septic shock. Concentration will be compared with blood concentration of postoperative patients suffering systemic inflammatory response syndrome (SIRS).

Recruitment information / eligibility
Status Recruiting
Enrollment 60
Est. completion date September 2022
Est. primary completion date June 2022
Accepts healthy volunteers No
Gender All
Age group 18 Years to 85 Years
Eligibility Inclusion Criteria: - Septic Shock Exclusion Criteria: - Age < 18 > 85 - no consent of caregiver - Trauma patients - Burn patients - Immunosuppression - Pregnancy - HIV- hepatitis infection

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
Germany University Hospital Tuebingen Tuebingen

Sponsors (1)
Lead Sponsor Collaborator
University Hospital Tuebingen

Country where clinical trial is conducted

Germany, 

Outcome
Type Measure Description Time frame Safety issue
Primary Semaphorin 1 to 7 in plasma of septic patients Concentration of Semaphorin in plasma of 60 sepsis patients [pg/ml]. 12 months
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