Inflammation Clinical Trial
Official title:
Quantitative Comparison of the Efficacy of Subtenon 20-mg Triamcinolone Injection With 0.1% Dexamethasone Eye Drop in Controlling Intraocular Inflammation After Phacoemulsification
Phacoemulsification is a quick method with less complication for cataract surgery. Due to the use of ultrasonic energy, it produced more post-operative inflammation than other methods. Many routes of steroid had been used to control post-operative inflammation. The investigators here compare the efficacy of single depot steroid subtenon injection (20-mg triamcinolone) with four-time-a-day steroid eye drop (0.1% dexamethasone) in controlling inflammation after uneventful phacoemulsification.
Cataract is one of the most common causes of blindness in the world. Surgical removal of
lens is the only treatment for cataract, which now shifts from extracapsular cataract
extraction to phacoemulsification. Although phacoemulsification provides faster operating
time and gives better optical result and rapid recovery to the patient, it causes more
inflammation post-operatively compare with extracapsular cataract extraction.
Corticosteroids eye drops are mainly use to control intraocular inflammation after the
surgery.
Other routes of corticosteroids have been introduced to increase the intraocular level and
to increase the patient's compliance. Subtenon triamcinolone injection is easy and safe.
Antiinflammatory effect of single subtenon triamcinolone injection lasts about 4-6 weeks.
This method has been used in combination with corticosteroid eye drop to control the
inflammation after cataract surgery in uveitic patients. It shows potency in controlling of
intraocular inflammation with lower rate of increasing the intraocular pressure. The
investigators here quantitatively compare the efficacy of subtenon 20-mg triamcinolone
injection with 0.1% dexamethasone eye drop in controlling intraocular inflammation after
uneventful phacoemulsification.
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Subject), Primary Purpose: Treatment
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