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Inflammatory Responses to Acute and Chronic Opioid Exposure in Humans

Inflammation Clinical Trial

Official title:
Inflammatory Responses to Acute and Chronic Opioid Exposure in Humans

Clinical Trial Summary

We aim to examine the extent to which inflammation is affected by acute and chronic opioid exposure.

Clinical Trial Description

We are interested in learning how the immune system and the inflammation process is effected by acute and chronic opioid exposure. Preliminary evidence in animal models show that acute opioid exposure leads to decreased inflammatory responses, while chronic opioid exposure causes increased inflammatory responses, as measured by local cytokine release at the site of injury. Translating these findings to humans will lead to important new mechanistic knowledge that may ultimately improve our ability to treat pain. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01749826
Study type Interventional
Source Stanford University
Contact
Status Terminated
Phase N/A
Start date January 2010
Completion date July 2013
View Details
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