The Effects of Resveratrol Supplementation on Measurements of Health and Human Performance

Inflammation Clinical Trial

— MUresv  

Official title:

The Effects of Resveratrol Supplementation on Measurements of Health and Human Performance

Clinical Trial Details — Status: Active, not recruiting

Administrative data

• NCT number: NCT01244360
• Other study ID #: MU Smoliga Resveratrol
• Secondary ID: 2RESMU194218
• Status: Active, not recruiting
• Phase: N/A
• First received: November 17, 2010
• Last updated: June 1, 2011
• Start date: November 2010
• Est. completion date: June 2011

Study information

• Verified date: June 2011
• Source: Marywood University
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to examine the effects of resveratrol on health and human performance. The study will evaluate cognitive function and several indicators of physical health before and after taking a resveratrol supplement or a placebo for three weeks.

Description:

Measurements

• blood laboratory parameters

• cognitive assessment changes

• body composition changes

• vascular endothelial response

Recruitment information / eligibility

• Status: Active, not recruiting
• Enrollment: 44
• Est. completion date: June 2011
• Est. primary completion date: June 2011
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Both
• Age group: 45 Years to 75 Years

Eligibility

Inclusion Criteria:

• men and women between 45 and 75 years of age

• Normal heart rate and Blood pressure

• Ability to use personal computer interface

• Successful completion of physical activity readiness questionnaire

Exclusion Criteria:

• Cardiovascular disease, uncontrolled hypertension, lung disease

• inability to tolerate exercise

• have taken grape related supplement in past 12 months

• current use of drugs or dietary supplements to enhance exercise performance

• allergy to wine, grape juice or grape seed supplements

Study Design

Allocation: Randomized, Endpoint Classification: Safety Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Inflammation

Intervention

Dietary Supplement:
• resveratrol
Subject will take resveratrol supplement for 4 weeks, with optional additional 4 week treatment period.

Other:
• Placebo Comparator: Sugar Pill
Subject will take placebo for daily for 4 weeks, with optional additional 4 week treatment period.

Locations

Country	Name	City	State
United States	Marywood University	Scranton	Pennsylvania

Sponsors (1)

Lead Sponsor	Collaborator
Marywood University

Country where clinical trial is conducted

United States, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Vascular function	vascular response to stress will be measured using flow mediated dilation and ultrasound.	4 weeks, with option of additional 4 week treatment period	No
Secondary	Body fat percentage	Body fat percentage will be measured using a DEXA scan.	4 weeks, with optional additional 4 week treatment period	No
Secondary	inflammation biomarkers	Fasting blood draw	4 weeks, with optional additional 4 week treatment period	No
Secondary	cognitive function	cognitive function will be assessed using a validated computer based assessment tool	4 weeks, with optional additional 4 week treatment period	No