Postprandial Effects of Milk and Milk Constituents

Inflammation Clinical Trial

Official title:

The Effects of Milk and Milk Constituents on Postprandial Inflammation in Overweight Subjects

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00917878
• Other study ID #: MEC 08-3-096
• Status: Completed
• Phase: N/A
• First received: June 8, 2009
• Last updated: April 25, 2018
• Start date: March 2009
• Est. completion date: July 2009

Study information

• Verified date: September 2009
• Source: Maastricht University Medical Center
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to determine whether the addition of milk or the milk constituents calcium and protein to a high-fat breakfast affects the postprandial lipid and inflammatory response.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 16
• Est. completion date: July 2009
• Est. primary completion date: July 2009
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Male
• Age group: 18 Years to 70 Years

Eligibility

Inclusion Criteria:

• Body mass index (BMI) above 27 kg/m2

Exclusion Criteria:

• Smoking

• Diabetes mellitus

• Cardiovascular diseases

• Familial hypercholesterolemia or lipid lowering medication

• Severe conditions that might interfere with the study outcomes, such as COPD, asthma, rheumatoid arthritis, etc.

• Unstable body weight

• Abuse of alcohol or drugs

• Participation in another biomedical study during the past 30 days

• Having donated blood during the past 30 days

Related Conditions & MeSH terms

• Hyperlipidemia
• Hyperlipidemias
• Hyperlipoproteinemias
• Inflammation

Intervention

Dietary Supplement:
• Milk
500 mL low-fat milk added to high-fat meal
• Protein
Milk protein in 500 mL water added to high-fat meal
• Calcium
Milk calcium in 500 mL water added to high-fat meal
• Control
Lactose in 500 mL water added to high-fat meal

Locations

Country	Name	City	State
Netherlands	Maastricht University Medical Center	Maastricht

Sponsors (2)

Lead Sponsor	Collaborator
Maastricht University Medical Center	Nederlandse Zuivel Organisatie

Country where clinical trial is conducted

Netherlands, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Plasma inflammatory markers		6 h after meal
Secondary	Serum lipids		6 h after meal