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Lactobacillus Plantarum 299v in Colon Surgery — Lp 299v  

Inflammation Clinical Trial

Official title:
L Plantarum 299v to Patients Undergoing Colon Resection - a Randomized Placebo-Controlled Study

Clinical Trial Summary

Intestinal pathogenes are often involved in postoperative complications after colon surgery. Probiotic bacteria, i e live bacteria which have beneficial effects on the host when ingested, have been shown to reduce bacterial translocation in animal studies. However, in humans studies results have varied. The purpose with this study was to find whether high doses of Lactobacillus plantarum 299v affects the potentially pathogenic microflora of the gut, bacterial translocation and cell proliferation in patients undergoing planned colon surgery.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00695461
Study type Interventional
Source Skane University Hospital
Contact
Status Completed
Phase N/A
Start date January 2001
Completion date August 2006
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