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Inflammation Gum clinical trials

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NCT ID: NCT06329596 Not yet recruiting - Dysbiosis Clinical Trials

Microbiome Alterations With Xylitol (MAX) in Pregnancy

MAX
Start date: June 13, 2024
Phase: N/A
Study type: Interventional

The purpose of this study is to understand if chewing xylitol-gum initiated before 20 weeks of pregnancy and continued until delivery affects the bacteria that are found in the oral and vaginal cavities, signs of inflammation within the gingiva of the oral cavity, the health of the tissues in the mouth (clinical parameters of periodontal disease), and the bacteria in the mouth and gut of newborns among pregnant individuals in Malawi.

NCT ID: NCT05928546 Not yet recruiting - Inflammation Gum Clinical Trials

Effect of Quercetin in Treatment of Periodontitis

Start date: February 20, 2024
Phase: Phase 1
Study type: Interventional

Periodontitis is an immune-inflammatory disease affecting the supporting structures of the teeth. It is a disease of multifactorial etiology, with microbial, genetic, environmental and host factors involved, with the release of oxygen-free radicals by the inflammatory cells. Quercetin, have shown potential antimicrobial activity, lowering of inflammatory markers, cholesterol reduction and inhibiting bone loss. However, this data has largely been obtained from in vitro and animal studies, but data from human studies are limited.

NCT ID: NCT05398770 Not yet recruiting - Inflammation Clinical Trials

Randomized Clinical Trial (RCT) on the Effect of Vitamin D Supplement Prior to Non-surgical Periodontal Therapy: a Feasibility Trial

Start date: August 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to test the feasibility i. e. to examine all aspects necessary for the implementation of a future randomized clinical trial that aims to determine whether non-surgical periodontal treatment can be improved by concomitant intake of vitamin D.