Infertility Clinical Trial
Official title:
Serum Anti-Müllerian Hormone Levels and Its Association With Aneuploidy Rates in Human Blastocysts
| NCT number | NCT05723016 |
| Other study ID # | AMH 2023 |
| Secondary ID | |
| Status | Completed |
| Phase | |
| First received | |
| Last updated | |
| Start date | January 1, 2018 |
| Est. completion date | December 31, 2022 |
| Verified date | February 2023 |
| Source | Clinica de la Mujer Medicina Reproductiva, Chile |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | |
| Study type | Observational |
The goal of this observational study is to determine is there an association between the rates of aneuploidy and the different ranges of serum Antimullerian hormone (AMH) levels. Retrospective, single-centre study of patients undergoing IVF and preimplantation genetic testing with aneuploidy at the blastocyst stage between January 2018 and December 2022.
| Status | Completed |
| Enrollment | 300 |
| Est. completion date | December 31, 2022 |
| Est. primary completion date | December 31, 2022 |
| Accepts healthy volunteers | No |
| Gender | Female |
| Age group | N/A and older |
| Eligibility | Inclusion Criteria: - All started cycles planned to be followed by preimplantation genetic testing for aneuploidies (PGT-A). PGT-A is proposed to the couples for the following reasons: advanced maternal age, recurrent miscarriage, repeated implantation failure or severe male infertility factor; it is also offered to all patients with a good prognosis who desired information regarding the ploidy status of their embryos. Exclusion Criteria: - Data from oocyte donation cycles |
| Country | Name | City | State |
|---|---|---|---|
| Chile | Clinica de la Mujer Medicina Reproductiva | Viña Del Mar | Valparaíso |
| Lead Sponsor | Collaborator |
|---|---|
| Clinica de la Mujer Medicina Reproductiva, Chile |
Chile,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Aneuplody rate | 4 years | ||
| Secondary | Clinical pregnancy rate | 4 years | ||
| Secondary | Miscarriage rate | 4 years |
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