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NCT03989843 Clinical Trial

Impact of Embryo Cryopreservation on Birth Weight

Infertility Clinical Trial

Official title:
Is Cryopreserved Embryo Replacement is Associated With Higher Birthweight Compared With Fresh Embryo ? Sibling Embryo Cohort Study

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT03989843
Other study ID # RECHMPL19_0306
Secondary ID
Status Completed
Phase
First received
Last updated
Start date May 1, 2007
Est. completion date June 30, 2015

Study information
Verified date June 2019
Source University Hospital, Montpellier
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Birth weight (BW) is higher after frozen embryo transfer (FET) than after fresh embryo replacement. No study has compared the BW of siblings conceived using the same oocyte/embryo cohort. The aim of this study was to determine whether the freezing-thawing procedure is involved in such difference.

Recruitment information / eligibility
Status Completed
Enrollment 183
Est. completion date June 30, 2015
Est. primary completion date June 1, 2015
Accepts healthy volunteers No
Gender Female
Age group 18 Years to 43 Years
Eligibility Inclusion Criteria:

- sibling pairs where fresh embryo replacement resulting in a singleton live birth was followed by transfer of one or two frozen embryos from the same cohort that resulted in a singleton live birth, between May 2007 and June 2015.

Exclusion Criteria:

- Twin pregnancies and stillbirths were excluded. If the BW of at least one sibling was unknown, the pair was not included in the study.

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
France Uh Montpellier Montpellier

Sponsors (1)
Lead Sponsor Collaborator
University Hospital, Montpellier

Country where clinical trial is conducted

France, 

Outcome
Type Measure Description Time frame Safety issue
Primary birthweight change after FET than after fresh embryo transfer 1 day
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