Cleavage Pattern of Embryos and Oxidative Parameters

Infertility Clinical Trial

Official title:

Is Abnormal Cleavage Pattern of Embryos Associated With Different Oxidative Parameters Compared With That of Normally Cleaving Embryos? A Prospective Cohort Study

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT03791931
• Other study ID #: CMC 18-0087-CTIL
• Status: Recruiting
• Phase: N/A
• Start date: July 7, 2019
• Est. completion date: April 1, 2021

Study information

• Verified date: February 2020
• Source: Carmel Medical Center
• Contact: Zofnat Wiener, MD
• Phone: 97248250335
• Email: wiener_zofnat[@]clalit.org.il
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

To investigate prospectively whether embryos with abnormal cleaving pattern have different oxidative parameters from normally cleaving embryos, and to analyze whether these parameters have an association with demographic, laboratory and clinical parameters including treatment outcome.

Description:

To investigate prospectively whether embryos with abnormal cleaving pattern have different oxidative parameters from normally cleaving embryos, and to analyze whether these parameters have an association with demographic, laboratory and clinical parameters including treatment outcome.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 200
• Est. completion date: April 1, 2021
• Est. primary completion date: January 1, 2021
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 45 Years

Eligibility

Inclusion Criteria:

• Patients undergoing IVF for the treatment of infertility

Exclusion Criteria:

• Age <18 or >45 years old

• Patients with no embryos with direct cleavage

Related Conditions & MeSH terms

• Infertility

Intervention

Diagnostic Test:
• oxidative stress measurement
oxidative stress measurement

Locations

Country	Name	City	State
Israel	Carmel Medical Center	Haifa

Sponsors (1)

Lead Sponsor	Collaborator
Carmel Medical Center

Country where clinical trial is conducted

Israel, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	implantation rate	Implantation rate (positive BHCG)	1 year
Primary	clinical pregnancy rate	Clinical pregnancy as defined by appearance of gestational sac on ultrasound	1 year