Does the Embryo Transfer Technique Affect the Success of in Vitro Fertilization?

Infertility Clinical Trial

Official title:

Comparison of IVF Success Rates Between Different Embryo Transfer Techniques: Afterload Technique and Trial Followed by Transfer Technique

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT03756857
• Other study ID #: AcibademKD
• Status: Recruiting
• Phase: N/A
• Start date: January 21, 2019
• Est. completion date: December 2021

Study information

• Verified date: March 2021
• Source: Acibadem Kadiköy Hospital
• Contact: Elif Esra UYAR, MD
• Phone: +902166494444
• Email: esra.uyar[@]acibadem.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Prospective, open, randomized, parallel, two-arm trial to compare the clinical pregnancy rate between most commonly used two embryo transfer techniques: trial followed by transfer technique and afterloading technique

Description:

Eligible patients will be informed about the possibility of participating in the clinical trial in the beginning of treatment and on the day ET, a signed consent form will be collected from those recipients who confirmed their participation. These patients will be randomized immediately before the ET procedure by sequentially numbered, opaque, sealed envelopes

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 200
• Est. completion date: December 2021
• Est. primary completion date: September 2021
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: 20 Years to 37 Years

Eligibility

Inclusion Criteria:

1. Patient has given written informed consent

2. BMI 18-30 kg/m2

3. < 2 previous failed IVF trials

4. At least two good quality embryos on the day of transfer

Exclusion Criteria:

1. Congenital uterine anomaly

2. Untreated endometrial polyp or fibroid distorting uterine cavity

3. Presence of hydrosalpinx 4.2 or more prior IVF trial failure

5.Moderate to severe endometriosis 6.Recurrent pregnancy loss history

Related Conditions & MeSH terms

• Assisted Reproductive Technology
• Infertility
• IVF

Intervention

Procedure:
• Afterload Transfer
Embryo transfer is done by using "afterload transfer" method
• Trial followed by transfer
Embryo transfer is done by using "afterload transfer" method

Locations

Country	Name	City	State
Turkey	Acibadem Altunizade Hospital, Unit of ART	Istanbul

Sponsors (1)

Lead Sponsor	Collaborator
Acibadem Kadiköy Hospital

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	clinical pregnancy rate	the presence of gestational sac on ultrasound	5-6 weeks after embryo transfer
Secondary	implantation rate	the number of gestational sacs divided by the number of embryos transferred	3-4 weeks after embryo transfer