Infertility Clinical Trial
Official title:
Latrunculin A Supplementation to ICSI Handling Medium
Verified date | May 2019 |
Source | Ibn Sina Hospital |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Vienna Consensus has identified 10% damage rate after ICSI as a competency value. Despite the highest quality embryologists doing ICSI, degeneration sometimes occurs due to oocyte factors such as the fragile membrane, etc. Latrunculin A serves to facilitate spindle or pronuclear transfer procedures helping to reduce the damage rate with no harm reported. Using Latrunculin A during ICSI could serve to rescue some oocytes from the degeneration allowing for more chances of viable zygotes,
Status | Completed |
Enrollment | 300 |
Est. completion date | April 30, 2019 |
Est. primary completion date | April 20, 2019 |
Accepts healthy volunteers | No |
Gender | Female |
Age group | 18 Years to 42 Years |
Eligibility |
Inclusion Criteria: - ICSI participants Exclusion Criteria: - |
Country | Name | City | State |
---|---|---|---|
Egypt | Banon Assiut | Assiut | |
Egypt | IbnSina IVF Center | Sohag |
Lead Sponsor | Collaborator |
---|---|
Ibn Sina Hospital |
Egypt,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | oocyte survival rate | 6 days of culture | ||
Secondary | fertilization rate | 6 days of culture | ||
Secondary | Blastocyst formation rate | 6 days of culture | ||
Secondary | Blastocyst quality rate | 6 days of culture | ||
Secondary | Clinical pregnancy rate | three months | ||
Secondary | Implantation rate | 7 weeks | ||
Secondary | Ongoing pregnancy rate | 12 weeks |
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