Induction of Ovulation Using Clomiphene Citrate and N-acetyl Cysteine Versus Letrozole

Infertility Clinical Trial

Official title:

Induction of Ovulation Using Clomiphene Citrate and N-acetyl Cysteine Versus Letrozole

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03241472
• Other study ID #: NACLET
• Status: Completed
• Phase: Phase 3
• First received: August 3, 2017
• Last updated: August 3, 2017
• Start date: February 2016
• Est. completion date: June 2017

Study information

• Verified date: August 2017
• Source: Assiut University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Infertility is defined as a couple's inability to become pregnant after one year of unprotected intercourse in women 35 years old and younger, and for six months in women over age 35 years. In any given year, about 15 percent of couples in North America and Europe who are trying to conceive are infertile

Recruitment information / eligibility

• Status: Completed
• Enrollment: 100
• Est. completion date: June 2017
• Est. primary completion date: May 2017
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 18 Years to 40 Years

Eligibility

Inclusion Criteria:

• All primary and secondary. Infertility due to anovulation

Exclusion Criteria:

• Male factor infertility, tubal factor.

• Endocrineopathy

• Hypothyrodism

• Morbid obesity

• Under weight

• Patient with previous surgery including drilling of ovary, Clomiphene Citrate resistant to ovulation.

Related Conditions & MeSH terms

• Infertility

Intervention

Drug:
• Letrozole
oral tablets 5 mg
• Clomiphene Citrate plus N acetyl cystine
Clomiphene Citrate 100 mg oral tablets+ N acetyl cystiene 600 mg

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Assiut University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	rate of ovulation	ultrasound evaluation	3 months