Does Transfer of Poor-quality Embryos With Good-quality Embryos Improve Pregnancy Outcome in Women Undergoing IVF/ICSI?

Infertility Clinical Trial

Official title:

Does Transfer of Poor-quality Embryos With Good-quality Embryos Improve Pregnancy Outcome in Women Undergoing IVF/ICSI?

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03113097
• Other study ID #: DAT-055
• Status: Completed
• Phase: N/A
• First received: April 10, 2017
• Last updated: April 10, 2017
• Start date: June 2014
• Est. completion date: March 2017

Study information

• Verified date: April 2017
• Source: Ain Shams University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Women planned to undergo blastocyst-stage embryo transfer after IVF/ICSI were randomized into 2 groups:

• group I: women who had only good-quality embryo transfer.

• group II: women who had both good-quality and poor-quality embryo transfer.

primary outcome was ongoing clinical pregnancy rate

Recruitment information / eligibility

• Status: Completed
• Enrollment: 627
• Est. completion date: March 2017
• Est. primary completion date: December 2016
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 20 Years to 35 Years

Eligibility

Inclusion Criteria:

• women undergoing primary IVF/ICSI cycles for tubal factor/unexplained infertility and had blastocyst-stage ET

Exclusion Criteria:

• cleavage-stage ET.

• women who had no good-quality embryos to transfer

• women who had known poor endometrial receptivity

Related Conditions & MeSH terms

• Infertility

Intervention

Other:
• Embryo transfer
Transfer of different qualities of embryos at blastocyst stage

Locations

Country	Name	City	State
n/a

Sponsors (2)

Lead Sponsor	Collaborator
Ain Shams University	Dar El Teb Institute

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Ongoing clinical pregnancy rate	viable intrauterine pregnancy ongoing beyond 12 weeks of gestation	12 weeks
Secondary	Biochemical pregnancy rate	positive serum hCG	2 weeks after ET
Secondary	Clinical pregnancy rate	sonographic detection of viable intrauterine gestational sac	4 weeks after ET
Secondary	Multiple pregnancy rate	No. of intrauterine gestational sacs	4-6 weeks after ET
Secondary	Ectopic pregnancy rate	Extrauterine pregnancy	6 weeks after ET