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NCT02806934 Clinical Trial

TNF Polymorphism and Implantation Rate

Infertility Clinical Trial

Official title:
Tumor Necrosis Factor-308 Polymorphism a Embryo Implantation Rate in Women Undergoing in Vitro Fertilization

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT02806934
Other study ID # 08-API-01
Secondary ID
Status Completed
Phase N/A
First received May 27, 2016
Last updated June 20, 2016
Start date June 2009
Est. completion date December 2013

Study information
Verified date June 2016
Source Centre Hospitalier Universitaire de Nice
Contact n/a
Is FDA regulated No
Health authority France: The Commission nationale de l’informatique et des libertés
Study type Observational

Clinical Trial Summary

Do TNF-308 and -238 polymorphisms impact the embryo implantation rate after in vitro fertilization (IVF) in women without female infertility factor ?

Description:

This study was performed in order to verify whether TNF-308 allele was associated with a higher implantation rate and multiple pregnancy rates in women without known infertility factors after ovarian hyperstimulation with exogenous FSH for IVF

Recruitment information / eligibility
Status Completed
Enrollment 120
Est. completion date December 2013
Est. primary completion date December 2013
Accepts healthy volunteers No
Gender Female
Age group 18 Years to 37 Years
Eligibility Inclusion Criteria:

- Women

- normal karyotype,

- age under 38 years

- serum follicle-stimulating hormone (Day-3 FSH) levels below 10 UI/l

Exclusion Criteria:

- age under 18 years

Study Design

Observational Model: Case-Only, Time Perspective: Prospective

Related Conditions & MeSH terms

Intervention

Procedure:
• biological and ultrasound test
biological and ultrasound test 20 days after implantation in order to see the implantation rate

Locations
Country Name City State
France Nice University Hospital Nice

Sponsors (1)
Lead Sponsor Collaborator
Centre Hospitalier Universitaire de Nice

Country where clinical trial is conducted

France, 

Outcome
Type Measure Description Time frame Safety issue
Primary Implantation rate by biological test 20 days after implantation No
Primary Implantation rate by ultrasound test 20 days after implantation No
See also
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