Infertility Clinical Trial
Official title:
LH Hormone Pulsation in the Luteal Phase in GnRH Antagonist IVF Cycles Triggered by GnRH Agonist for Final Oocyte Maturation
Monitoring the LH pulsatility during the Luteal phase in GnRH antagonist IVF cycles triggered by GnRH agonist for final oocyte maturation.
About two decades ago the GnRH antagonist has been used in IVF cycles to prevent premature
LH surge. In recent review GNRH antagonist has been found comparable to GnRH agonist in term
of live birth rate but with reduced risk of OHSS. another advantage of using GnRH antagonist
is the ability to use GnRH agonist for final oocyte maturation which has been shown to
nearly eliminate the risk of OHSS. The exact mechanism of this risk reduction is still
unknown.
Our aim is to do a frequent blood tests every 20 minutes for 6 hours duration in the day of
ovum pick up or the day of embryo transfer to measure the level of LH, estradiol and
progesterone in women triggered with GnRH agonist for final oocyte maturation.
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Observational Model: Cohort, Time Perspective: Prospective
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