Infertility Clinical Trial
Official title:
Effectiveness of Oral Versus Vaginal Misoprostol Before Office Hyteroscopy in Infertile Patients
The role of hysteroscopy in infertility investigation is to detect possible intrauterine
changes that could interfere with implantation or growth or both of the conceptus, with the
invention of miniature hysteroscope, it is possible to perform hysteroscopy in an office
setting (Outpatient hysteroscopy; OH), for diagnostic and certain therapeutic intervention.
It is currently acknowledged as the 'gold standard' investigation of the intrauterine
abnormalities.
Cervical priming prior to diagnostic hysteroscopy softens the cervix and lessens the force
needed for dilation, thereby potentially reducing the probability of procedural complication
such as uterine perforation, cervical laceration, failure to dilate, and creation of a false
track that can occur during cervical entry.
Misoprostol is a prostaglandin El analogue, that can be administered either orally or
vaginally, that can cause cervical ripening by inducing collagenolytic activity and
synthesis of proteoglycans.
n/a
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Diagnostic
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