Infertility Clinical Trial
Official title:
Evaluation the Effect of Intrauterine Injection of Human Chorionic Gonadotropin Injection (hCG) Before Frozen Embryo Transfer on Implantation, Clinical Pregnancy and Miscarriage Rates: Double Blind Randomized Clinical Trial ,Phase 3
Verified date | May 2016 |
Source | Royan Institute |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The present study is designed as a pilot study with 150 patients in each group. Data collection form will be filled by the researcher who does not know the type of intervention in each group. Data analysis will be done through descriptive and perceptive statistical methods by using SPSS software version 20 for windows
Status | Completed |
Enrollment | 180 |
Est. completion date | December 2018 |
Est. primary completion date | December 2018 |
Accepts healthy volunteers | No |
Gender | Female |
Age group | 20 Years to 40 Years |
Eligibility |
Inclusion Criteria: 1. Patients with history of one fresh embryo transfer failure 2. Patients with Primary infertility 3. Patients with at least one embryo with excellent quality Exclusion Criteria: 1. Female age over 40 years old 2- Severe male factor (Azoospermia) 3- Endometriosis diagnosis and the presence of hydrosalpinges 4- Uterine factor ( polyps, myoma and previous myomectomy, …) 5- Patients with polycystic ovarian syndrome diagnosis 6- Cases with pre-implantation genetic diagnosis (PGD)indication 7- Cases with difficult embryo transfer or use of Tenaculum 8- Patients with repeated implantation failures and repeated miscarriages. 9- Female smokers |
Country | Name | City | State |
---|---|---|---|
Iran, Islamic Republic of | Royan Institute | Tehran |
Lead Sponsor | Collaborator |
---|---|
Royan Institute |
Iran, Islamic Republic of,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Clinical pregnancy rate | Evaluation the rate of clinical pregnancy 4-6 weeks after embryo transfer | 4 weeks | |
Secondary | Ongoing pregnancy | Evaluation the Ongoing pregnancy 20 weeks after pregnancy | 20 weeks | |
Secondary | early miscarriage rate | Evaluation thepregnancy loss under 12 weeks of gestational age | 12 weeks | |
Secondary | Chemical pregnancy rate | Evaluation the Chemical pregnancy rate 2 weeks after embryo transfer. | 2 weeks | |
Secondary | Late miscarriage rate20 weeks | Evaluation the pregnancy loss under 20 weeks of gestational age | 20 weeks |
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