Timing of HCG Administration in IUI Cycles

Infertility Clinical Trial

Official title:

Timing of Human Chorionic Gonadotropin Administration in Intrauterine Insemination Cycles

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT02330705
• Other study ID #: MIE3
• Status: Recruiting
• Phase: Phase 4
• Start date: January 2015
• Est. completion date: August 2019

Study information

• Verified date: January 2019
• Source: Mansoura University
• Contact: Mohamed I Eid, Dr
• Phone: +201225401274
• Email: dr_moh_eid[@]yahoo.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Evaluation of the effect of altering the timing of human chorionic gonadotropin (HCG) administration on the clinical pregnancy rate in intrauterine insemination (IUI) cycles.

Description:

Women will be randomly divided into 3 groups; the first group will undergo IUI at the time HCG administration, the second group will undergo IUI 12 hours after HCG administration and the third group will undergo IUI 34-36 hours after HCG administration.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 225
• Est. completion date: August 2019
• Est. primary completion date: July 2019
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 20 Years to 35 Years

Eligibility

Inclusion Criteria:

• Mild male factor infertility or unexplained infertility.

Exclusion Criteria:

• Advanced male factor infertility.

• Polycystic ovary syndrome (PCOS) as defined by the Rotterdam criteria.

• Endometriosis.

• Tubal disease.

• Uterine abnormalities or myoma.

• Previous uterine surgery.

• Metabolic or hormonal abnormalities.

Related Conditions & MeSH terms

• Infertility

Intervention

Drug:
• HCG
Women will be given HCG before IUI

Locations

Country	Name	City	State
Egypt	Fertility care unit (FCU) in Mansoura University Hospitals	Mansourah	Dakahlia
Egypt	Private fertility care centers	Mansourah	Dakahlia

Sponsors (1)

Lead Sponsor	Collaborator
Mohamed Ibrahem Eid

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Clinical pregnancy rate	Number of clinical pregnancies (defined as presence of at least one intrauterine gestational sac with fetal pole and cardiac activity on TVS scan at 4-6 weeks after IUI) divided by the number of IUI cycles	4-6 weeks after IUI