Infertility Clinical Trial
Official title:
Controlled Ovarian Stimulation With Recombinant Follicle Stimulating Hormone Plus Recombinant Luteinizing Hormone vs. Human Menopausal Gonadotropin in In Vitro Fertilization: Retrospective Analysis of Real Life Data
Verified date | December 2014 |
Source | University of Turin, Italy |
Contact | n/a |
Is FDA regulated | No |
Health authority | Italy: Ethics Committee |
Study type | Observational |
The purpose of this retrospective study was to assess the outcome of In Vitro Fertilization (IVF) according to the type of medication used for controlled ovarian stimulation (COS). The study compared the pregnancy rate obtained by 398 patients who had received COS with recombinant Follicle Stimulating Hormone (rFSH) plus recombinant Luteinising Hormone (rLH) in 2:1 ratio vs. the one observed in 450 patients who had been treated with human Menopausal Gonadotropin (hMG), stratifying results according to the number of retrieved oocytes.
Status | Completed |
Enrollment | 848 |
Est. completion date | August 2014 |
Est. primary completion date | August 2014 |
Accepts healthy volunteers | No |
Gender | Female |
Age group | 20 Years to 45 Years |
Eligibility |
Inclusion Criteria: - infertility - need to undergo IVF - circulating basal FSH above 6.5 UI/l - circulating AMH 0.1-2 ng/ml - basal antral follicle count between 3 and 15 Exclusion Criteria: - circulating basal FSH below 6.5 UI/l - circulating AMH below 0.1 ng/ml or above 2 ng/ml - basal antral follicle count below 3 or above 15 |
Observational Model: Case Control, Time Perspective: Retrospective
Country | Name | City | State |
---|---|---|---|
Italy | Physiopathology of Reproduction and IVF Unit, S. Anna Hospital | Torino |
Lead Sponsor | Collaborator |
---|---|
University of Turin, Italy |
Italy,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Pregnancy rate per embryo transfer (PR/ET) | First transvaginal US examination three weeks after a positive pregnancy test | No |
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