Infertility Clinical Trial
— RIFOfficial title:
Effects of Granulocyte - Macrophage Colony - Stimulating Factor (GM-CSF) Supplementation in Embryo Culture in Patients With Repeated Implantation Failure
Verified date | September 2014 |
Source | Vietnam National University |
Contact | n/a |
Is FDA regulated | No |
Health authority | Vietnam: Vietnam National University |
Study type | Interventional |
The purpose of this study was to investigate the potential effects of Granulocyte-Macrophage Stimulating-Colony Factor (GM-CSF) supplementation in embryo culture for patients with repeated implantation failure (RIF)
Status | Completed |
Enrollment | 60 |
Est. completion date | August 2014 |
Est. primary completion date | March 2014 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Female |
Age group | 18 Years to 40 Years |
Eligibility |
Inclusion Criteria: - Normal ovarian reserve (AMH > 1.1 ng/ml) - Regular menstrual cycle (25 - 34 days) - Clear informations about at least 3 latest IVF/ET - Fresh embryo transfer in this cycle - Endometrial thickness of 10 mm or more Exclusion Criteria: - Undergo oocyte donation or in vitro maturation (IVM) cycles - Using frozen or surgically retrieved sperm - Adenomyosis, Uterine anomaly, uterine fibroid, hydrosalpinges - In participation in other studies/interventions |
Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
Vietnam | An Sinh Hospital | Ho Chi Minh |
Lead Sponsor | Collaborator |
---|---|
Vietnam National University |
Vietnam,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | ongoing pregnancy rate | 12 week of gestation | No | |
Secondary | Implantation rate | 7 week of gestation | No | |
Secondary | clinical pregnancy rate | 7 week of gestation | No | |
Secondary | top quality embryo rate | 44 hours after insemination | No |
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