Infertility Clinical Trial
Official title:
Effect of Hyaluronan Enriched Embryo Transfer Media on IVF Outcome
Verified date | March 2014 |
Source | Semmelweis University |
Contact | n/a |
Is FDA regulated | No |
Health authority | Hungary: Institutional Ethics Committee |
Study type | Observational |
Prospective randomized double blind comparison of hyaluronan enriched embryotransfer media
and conventional embryotransfer media in human IVF treatments. Embryos selected for transfer
are incubated in a culture media containing high concentration of hyaluronan or low
concentration of hyaluronan.
Primary outcome: implantation and pregnancy rates
Status | Completed |
Enrollment | 580 |
Est. completion date | December 2013 |
Est. primary completion date | August 2012 |
Accepts healthy volunteers | No |
Gender | Female |
Age group | 18 Years to 48 Years |
Eligibility |
Inclusion Criteria: - Infertile patients - entering in vitro fertilization treatment - at least 1 embryo transferred Exclusion Criteria: - IVF treatment with donated oocytes - No embryo available for transfer |
Observational Model: Cohort, Time Perspective: Prospective
Country | Name | City | State |
---|---|---|---|
Hungary | Semmelweis University First Department of Obstetrics and Gynecology | Budapest |
Lead Sponsor | Collaborator |
---|---|
Peter Fancsovits, Ph.D. |
Hungary,
Bontekoe S, Heineman MJ, Johnson N, Blake D. Adherence compounds in embryo transfer media for assisted reproductive technologies. Cochrane Database Syst Rev. 2014 Feb 25;2:CD007421. doi: 10.1002/14651858.CD007421.pub3. Review. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Clinical pregnancy rate | Number of clinical pregnancies (gestational sacs visible by ultrasound examination) divided by the number of embryotransfers | 5 weeks after embryo transfer | No |
Primary | Implantation rate | Number of embryos implanted (No. of gestational sacs) divided by the number of embryos implanted | 5 weeks after embryotransfer | No |
Secondary | Multiple pregnancy rate | Number of multiple pregnancies divided by the number of embryotransfers | 5 weeks after embryotransfer | No |
Secondary | Delivery rate | Number of delivery divided by the number of embryo transfers | 40 weeks after embryo transfer | No |
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