Infertility Clinical Trial
Official title:
Reproductive Medicine Network Biologic Specimen Repository
The Reproductive Medicine Network (RMN) is a nationwide cooperative network of 7 clinical
sites and a data coordination center, and is sponsored in 5 year increments by The Eunice
Kennedy Shriver National Institute for Child Health and Human Development (NICHD). The RMN
is charged with designing, implementing and publishing high quality clinical research in
reproductive medicine. It has been in existence for over 15 years and has performed several
seminal clinical trials that have fundamentally changed clinical practice in this field. In
addition, many worthy ancillary protocols have been generated and published.
It is this latter fact, as well as the continued interest by investigators both inside and
outside the RMN for access to DNA or serum samples from the previously performed trials,
that has motivated the present investigators to proactively begin a biologic samples
repository from the ongoing and pending RMN clinical trials. Ideally, this repository would
allow investigators to seamlessly access trial samples for many years into the future, and
thus greatly amplify the use of resources and the impact of the RMN.
Status | Completed |
Enrollment | 1640 |
Est. completion date | January 2015 |
Est. primary completion date | November 2014 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | N/A and older |
Eligibility |
Inclusion Criteria: - Any subject of an RMN clinical trial and consents to participate in the repository is eligible for inclusion. Exclusion Criteria: |
Time Perspective: Prospective
Country | Name | City | State |
---|---|---|---|
United States | University of Michigan | Ann Arbor | Michigan |
United States | University of Colorado | Aurora | Colorado |
United States | University of Alabama Birmingham | Birmingham | Alabama |
United States | University of Vermont | Burlington | Vermont |
United States | Carolinas Medical Center | Charlotte | North Carolina |
United States | Wayne State University | Detroit | Michigan |
United States | Hackensack University | Hackensack | New Jersey |
United States | Pennsylvania State University College of Medicine | Hershey | Pennsylvania |
United States | University of Oklahoma Health Sciences Center | Oklahoma City | Oklahoma |
United States | University of Pennsylvania | Philadelphia | Pennsylvania |
United States | Virginia Commonwealth University, School of Medicine | Richmond | Virginia |
United States | University of Texas Health Science Center at San Antonio | San Antonio | Texas |
United States | University of California, San Francisco | San Francisco | California |
United States | Stanford University Medical Center | Stanford | California |
United States | University of Connecticut | Storrs | Connecticut |
Lead Sponsor | Collaborator |
---|---|
Yale University | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), Penn State University, University of Colorado, Denver, University of Michigan, University of Pennsylvania, University of Texas, University of Vermont, Wayne State University |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Proportion of subject who accepted participation | 4.2 years | No |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT03607409 -
Role of Inhibin A as Biomarker for Ovarian Response for IVF Treatment
|
||
Recruiting |
NCT02312076 -
GnRHa for Luteal Phase Support in Long GnRHa Protocol Cycles
|
Phase 4 | |
Terminated |
NCT02161861 -
Improvement of IVF Fertilization Rates, by the Cyclic Tripeptide FEE - Prospective Randomized Study
|
N/A | |
Completed |
NCT03287479 -
Comparison of a Semi-automated Closed Vitrification System (Gavi®) With a Manual Open Vitrification Sytem (Cryotop®)
|
N/A | |
Terminated |
NCT03522350 -
Randomized Trial Comparing EmbryoScope With EmbryoScope+.
|
N/A | |
Completed |
NCT04496284 -
Embryo Transfer Outcomes After Vitrification With Slush Nitrogen Compared to Liquid Nitrogen
|
N/A | |
Completed |
NCT03623659 -
pArtiaL zonA pelluciDa Removal by assisteD hatchINg of Blastocysts
|
N/A | |
Completed |
NCT03895099 -
New Ovarian Stimulation With Random Start, Use of Progestin Protocol for Oocyte Donors
|
Phase 3 | |
Active, not recruiting |
NCT04142112 -
Randomized, Standard-Controlled, Study to Evaluate the Ohana IVF Sperm Preparation Kit, SPeRtility IVF Next Generation
|
N/A | |
Completed |
NCT03152643 -
Cumulative Live Birth Rates After Cleavage-stage Versus Blastocyst-stage Embryo Transfer
|
N/A | |
Recruiting |
NCT03683771 -
Assessment of Endometrial Pattern and Sub-endometrial Vascularity in ICSI Outcome
|
||
Recruiting |
NCT03161119 -
Comparing Two Different Embryo Transfer Catheters
|
N/A | |
Completed |
NCT04108039 -
Micronized Progesterone vs Gonadotropin-releasing Hormone (GnRH) Antagonist in Freeze-all IVF Cycles.
|
N/A | |
Completed |
NCT03678584 -
Supplementing Intracytoplasmic Sperm Injection Handling Medium With Chaetoglobosin A ( ICSI-CA)
|
N/A | |
Completed |
NCT03677492 -
Supplementing Intracytoplasmic Sperm Injection Handling Medium With Cytochalasin D ( ICSI-CD)
|
N/A | |
Completed |
NCT03678610 -
Handling Medium for ICSI With Ionomycin and Latrunculin A
|
N/A | |
Completed |
NCT03678558 -
Oocyte Vitrification Aided With Cytochalasin B
|
N/A | |
Completed |
NCT03678818 -
Supplementing Intracytoplasmic Sperm Injection Handling Medium With Latrunculin A (ICSI-LA)
|
N/A | |
Completed |
NCT03678597 -
Supplementing Intracytoplasmic Sperm Injection Handling Medium With Latrunculin B ( ICSI-LB)
|
N/A | |
Completed |
NCT03678571 -
Oocyte Vitrification Aided With Latrunculin A
|
N/A |