Embryo Transfer: Direct Versus Afterloading Trial

Infertility Clinical Trial

Official title:

Direct Transfer vs Previous Cervical Canalization Transfer ("Afterloading"): Randomized Clinical Trial.

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00824629
• Other study ID #: DEX001
• Status: Completed
• Phase: N/A
• First received: January 16, 2009
• Last updated: October 25, 2010
• Start date: October 2008
• Est. completion date: September 2010

Study information

• Verified date: August 2009
• Source: Institut Universitari Dexeus
• Contact: n/a
• Is FDA regulated: No
• Health authority: Spain: Ethics Committee
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to evaluate two types of embryo transfer procedure.

The investigators will compare direct embryo transfer against afterloading embryo transfer.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 400
• Est. completion date: September 2010
• Est. primary completion date: September 2010
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 18 Years to 42 Years

Eligibility

Inclusion Criteria:

• Patients in IVF/CICSI program

• Transfer day:2 or 3 after ovum pick-up

Exclusion Criteria:

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Infertility

Intervention

Procedure:
• Afterloading embryo transfer procedure
Afterloading embryo transfer procedure
• Direct embryo transfer procedure
Direct embryo transfer procedure

Locations

Country	Name	City	State
Spain	Departamento de Obstetricia Ginecologia y Reproducción. Institut Universitari Dexeus	Barcelona

Sponsors (1)

Lead Sponsor	Collaborator
Institut Universitari Dexeus

Country where clinical trial is conducted

Spain, 

References & Publications (6)

Coroleu B, Barri PN, Carreras O, Belil I, Buxaderas R, Veiga A, Balasch J. Effect of using an echogenic catheter for ultrasound-guided embryo transfer in an IVF programme: a prospective, randomized, controlled study. Hum Reprod. 2006 Jul;21(7):1809-15. Epub 2006 Mar 23. — View Citation

Coroleu B, Barri PN, Carreras O, Martínez F, Parriego M, Hereter L, Parera N, Veiga A, Balasch J. The influence of the depth of embryo replacement into the uterine cavity on implantation rates after IVF: a controlled, ultrasound-guided study. Hum Reprod. 2002 Feb;17(2):341-6. — View Citation

Coroleu B, Barri PN, Carreras O, Martínez F, Veiga A, Balasch J. The usefulness of ultrasound guidance in frozen-thawed embryo transfer: a prospective randomized clinical trial. Hum Reprod. 2002 Nov;17(11):2885-90. — View Citation

Coroleu B, Carreras O, Veiga A, Martell A, Martinez F, Belil I, Hereter L, Barri PN. Embryo transfer under ultrasound guidance improves pregnancy rates after in-vitro fertilization. Hum Reprod. 2000 Mar;15(3):616-20. — View Citation

Matorras R, Mendoza R, Expósito A, Rodriguez-Escudero FJ. Influence of the time interval between embryo catheter loading and discharging on the success of IVF. Hum Reprod. 2004 Sep;19(9):2027-30. Epub 2004 Jun 10. — View Citation

Neithardt AB, Segars JH, Hennessy S, James AN, McKeeby JL. Embryo afterloading: a refinement in embryo transfer technique that may increase clinical pregnancy. Fertil Steril. 2005 Mar;83(3):710-4. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Clinical pregnancy		8 weeks after embryo transfer	No
Secondary	Difficulty of embryo transfer		During embryo transfer procedure	No
Secondary	Duration of embryo transfer		During embryo transfer procedure	No

External Links

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