Ultrasound Guided Embryo Transfer: Abdominal Versus Transvaginal, a RCT

Infertility Clinical Trial

Official title:

Abdominal Versus Transvaginal Ultrasound Guided Embryo Transfer: Results of a Randomized Clinical Trial

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT00682071
• Other study ID #: 2003-311
• Secondary ID: IRB# 2003-311 (U
• Status: Completed
• Phase: N/A
• First received: May 16, 2008
• Last updated: October 1, 2015
• Start date: August 2003
• Est. completion date: June 2007

Study information

• Verified date: May 2008
• Source: University of Wisconsin, Madison
• Contact: n/a
• Is FDA regulated: No
• Health authority: United States: Institutional Review Board
• Study type: Observational

Clinical Trial Summary

Ultrasound (US) guided embryo transfer (ET) appears to improve pregnancy outcomes in IVF-ET. Most reports are done using a transabdominal (TAS) approach, in contrast to a transvaginal ultrasound (TVS) which does not require a full bladder. We sought to determine if either approach was better with respect to clinical outcomes.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 224
• Est. completion date: June 2007
• Est. primary completion date: June 2007
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: Female
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• All patients undergoing assisted reproductive cycles including autologous IVF, oocyte donation, and frozen embryo transfer (FET) cycles

Exclusion Criteria:

• Cases of severe ovarian hyper-stimulation requiring embryo cryopreservation and gestational surrogate cycles

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

• in Vitro Fertilization
• Infertility

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
University of Wisconsin, Madison

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	pregnancy rates for TAS and TVS ultrasound-guided ET groups		August 2003 to June 2007	No
Secondary	Length of time required for embryo transfer		August 2003 to June 2007	No
Secondary	differences between transferring physicians		August 2003 to June 2007	No
Secondary	multiple pregnancies		August 2003 to June 2007	No
Secondary	ectopic pregnancy rates		August 2003 to June 2007	No