Infertility Clinical Trial
Official title:
Study of Optimal Posology of Gonadotrophins in Patients With Insufficient Ovarian Response Due to Age
In In vitro fertilization (IVF) treatment, poor responder patients of more than 38 years old are randomized prospectively into two dosages of gonadotrophins. The outcome of treatment will be analyzed.
Women > 38 years, who had an insufficient response to stimulation with regular (for age)
posology of 225 IU of gonadotrophins (urinary or recombinant), in an agonist protocol will
be randomized prospectively into 2 groups:
300 IU versus 450 IU of Gonal-f® administered in a short agonist protocol. Insufficient
response is defined as: development of ≤ 4 mature follicles (of ≥ 16 mm) at time of hCG
administration.
Patient can be eligible for several cycles in same protocol.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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