Infertility Clinical Trial
Official title:
Half-Dose Depot Triptorelin Versus Reduced-Dose Daily Buserelin in a Long Protocol of Controlled Ovarian Stimulation for ICSI/ET
Verified date | April 2007 |
Source | Tehran University of Medical Sciences |
Contact | n/a |
Is FDA regulated | No |
Health authority | Iran: Ministry of Health |
Study type | Interventional |
The purpose of this study is to determine whether half-dose depot triptorelin are as effective as reduced-dose daily buserelin in the controlled ovarian stimulation for intracytoplasmic sperm injection and embryo transfer
Status | Completed |
Enrollment | 182 |
Est. completion date | December 2006 |
Est. primary completion date | |
Accepts healthy volunteers | No |
Gender | Female |
Age group | N/A to 35 Years |
Eligibility |
Inclusion Criteria: - Candidate for ICSI/ET - 35 years old or younger - Serum FSH less than 10 IU/l on day three of the previous menstrual cycle - No more than two previous IVF/ICSI attempts - No planned percutaneous epididymal sperm aspiration [PESA] - No planned testicular sperm extraction [TESE] - No known history or risk of severe hyperstimulation - No evidence of hydrosalpinx - No major systemic disease - No uterine abnormality - No previous ovarian surgery |
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double-Blind, Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
Iran, Islamic Republic of | Dr. Shariati Hospital | Tehran |
Lead Sponsor | Collaborator |
---|---|
Tehran University of Medical Sciences |
Iran, Islamic Republic of,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Number of retrieved oocytes | |||
Secondary | Number of days of gonadotropin stimulation | |||
Secondary | Number of hMG ampoules | |||
Secondary | Number of follicles at hCG administration | |||
Secondary | Quality of oocytes | |||
Secondary | Quality of embryos | |||
Secondary | Poor response rate | |||
Secondary | Oocyte fertilization rate | |||
Secondary | Ineffective intervention rate | |||
Secondary | Clinical pregnancy rate | |||
Secondary | Implantation rate | |||
Secondary | Biochemical pregnancy rate | |||
Secondary | Multiple pregnancy rate | |||
Secondary | Miscarriage rate | |||
Secondary | Ectopic pregnancy rate |
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