Infertility Clinical Trial
Official title:
Effects of Hormonal Infertility Treatment on Cognition in Pre-Menopausal Women
Verified date | November 2006 |
Source | National Institute on Aging (NIA) |
Contact | n/a |
Is FDA regulated | No |
Health authority | United States: Federal Government |
Study type | Observational |
The purpose of this study is to examine the effects of marked alterations in ovarian steroid hormones on cognitive functions in women. Sex hormones and stress hormones of women awaiting or undergoing in-vitro fertilization (IVF) will be compared with levels of women adopting children and women on oral contraceptives.
Status | Completed |
Enrollment | 80 |
Est. completion date | November 2006 |
Est. primary completion date | November 2006 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Female |
Age group | 25 Years and older |
Eligibility |
Inclusion Criteria: - Women 25 years and older, who are still ovulating - Residing in Maryland or the Washington DC metropolitan area - Healthy women in one of the following groups: - 1) beginning or currently undergoing IVF infertility treatments with GnRH-a alone, - 2) beginning or currently undergoing IVF infertility treatments with GnrH-a plus sex steroid stimulating hormones, - 3) going through the adoption process, or - 4) taking monophasic oral contraceptives for at least six months Exclusion Criteria: - English not the primary language - Women who are peri- or post-menopausal - Women who are currently taking anti-depressants or have a history of head injury or neurological/psychiatric condition - Groups 1 & 2 (IVF) - women who are undergoing Inter-uterine insemination as an infertility treatment - Group 3 (ADPT) - women who underwent hormonal infertility treatments within the previous 6 months - Group 4 (OC) - women on progesterone only (mini-pill) oral contraceptives |
N/A
Country | Name | City | State |
---|---|---|---|
United States | National Institute on Aging (NIA), Harbor Hospital | Baltimore | Maryland |
Lead Sponsor | Collaborator |
---|---|
National Institute on Aging (NIA) |
United States,
Harlow CR, Fahy UM, Talbot WM, Wardle PG, Hull MG. Stress and stress-related hormones during in-vitro fertilization treatment. Hum Reprod. 1996 Feb;11(2):274-9. — View Citation
Oddens BJ, den Tonkelaar I, Nieuwenhuyse H. Psychosocial experiences in women facing fertility problems--a comparative survey. Hum Reprod. 1999 Jan;14(1):255-61. — View Citation
Sherwin BB, Tulandi T. "Add-back" estrogen reverses cognitive deficits induced by a gonadotropin-releasing hormone agonist in women with leiomyomata uteri. J Clin Endocrinol Metab. 1996 Jul;81(7):2545-9. — View Citation
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