Infertility Indicated for ICSI Clinical Trial
— AIPRICSIOfficial title:
Role of Aromatase Inhibitor to Enhance Ovulation in Poor Responder During Induction With Short Antagonist Protocol in Cases of ICSI(Intracytoplasmic Sperm Injection) a Case Control Study
Verified date | September 2017 |
Source | Minia University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
study the effect of aromataze inhibitor induction together with short stimulation protocol by gonadotrphin releasing hormon antagonist in cases that expected to be poor responder before ICSI
Status | Completed |
Enrollment | 50 |
Est. completion date | September 3, 2017 |
Est. primary completion date | August 24, 2017 |
Accepts healthy volunteers | No |
Gender | Female |
Age group | 18 Years to 44 Years |
Eligibility |
Inclusion Criteria: - infertlity indicated for ICSI - Ovarian factor - Tubal factor - Unexplained infertility - poor responders Exclusion Criteria: - Expected high responder - Endometriosis - Male and uterine factors - Ovarian mass or cyst |
Country | Name | City | State |
---|---|---|---|
Egypt | Minia University | Minia |
Lead Sponsor | Collaborator |
---|---|
Minia University |
Egypt,
Mitwally MF, Casper RF. Aromatase inhibition improves ovarian response to follicle-stimulating hormone in poor responders. Fertil Steril. 2002 Apr;77(4):776-80. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Number of follicles per cycle that reach more than 17mm in diameter(quantity of ova) | measurement of the diameter of follicles by transvaginal ultrasoundand description of diameter in report | day of HCG injection | |
Primary | quality of ova | After ova picking up examination of all ova under microscope and report how many ova reach metaphase II (quality) if more than 3 ova reach metaphase II considered satisfactory quality of ova in the current cycle | day of ovum pick up | |
Secondary | pregnancy rate | presence of clinical pregnancy | 14 days after ovum pick up |