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NCT04654598 Clinical Trial

BPA Levels Relationship With IVF/ICSI Outcomes in Low Ovarian Reserve

Infertility, Female Clinical Trial

Official title:
Could the Consumption of Water From Plastic Bottles Affect the Embryo Grade and Clinical Pregnancy Rate Obtained With IVF/ICSI in Low Ovarian Reserve

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT04654598
Other study ID # 2019/19
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date April 1, 2019
Est. completion date September 30, 2019

Study information
Verified date December 2020
Source Sanliurfa Mehmet Akif Inan Education and Research Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The relationship between BPA elevation in urine, blood, and follicle fluid and embryo quality, IVF/ICSI outcomes.

Recruitment information / eligibility
Status Completed
Enrollment 74
Est. completion date September 30, 2019
Est. primary completion date September 30, 2019
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Female
Age group 25 Years to 45 Years
Eligibility Inclusion Criteria: - patients who underwent IVF due to low ovarian reserve - patients provided urine, blood, and follicle fluid (FF) samples on the oocyte retrieval day - patients who did not smoke or use alcohol - patients did not work in the plastic industry Exclusion Criteria: - patients who underwent IVF due to unexplained infertility or tubal factor or male factor indications - patients diagnosed with endometriosis - patients with freeze-all cycles - patients having previous ovarian surgery - women with metabolic disease (such as hypertension or diabetes mellitus) - patients with a known genetic problem (male or female)

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• BPA levels
BPA (bisphenol A) in urine, blood and follicle fluid samples

Locations
Country Name City State
Turkey Nefise Nazli YENIGUL Sanliurfa

Sponsors (1)
Lead Sponsor Collaborator
Nefise Nazli YENIGUL

Country where clinical trial is conducted

Turkey, 

Outcome
Type Measure Description Time frame Safety issue
Primary Exposure to BPA Concentrations of Bisphenol A (BPA) will be quantified in the urine, blood plasma, and follicular fluid (individual and pooled samples) by use of ELISA test in women with low ovarian reserve 6 month
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