Infertility, Female Clinical Trial
Official title:
Chung Shan Medical University Hospital
The aim of this study was to compare the clinical outcomes between fresh embryo and frozen
embryo transfer in in vitro fertilization (IVF). All frozen embryo was vitrified at
pronuclear stage (2PN) and cultured to cleavage embryos for transfer.
This is a retrospective study. All IVF cycles were included in this study and further divided
into fresh and frozen embryo transfer groups. The collection data including: stimulation
protocols, medicines, blood test results, pregnancy test and all clinical data. The primary
outcome is pregnancy rate and secondary outcome is implantation rate.
Study design
Study progress:
Stage 1: collection of all data from frozen embryo transfer and fresh embryo transfer groups.
Stage 2: selection data and check the delivery outcomes Stage 3: analysis data and
presentation. Including criteria: all patients who underwent IVF. Excluding criteria: No.
Statistics analysis: chi-test, t-test
Assessment point:
Primary endpoint: pregnancy rate Secondary endpoint: implantation rate Withdraw criteria: not
application. Treatments: not application. Collection number: 500 patients. Scheduled trial
period: 2017.05.01~2018.04.30
Expected research results:
The implantation rate in frozen embryo transfer group which vitrified at 2PN stage is higher
than fresh embryo transfer.
The pregnancy rate in frozen embryo transfer group which vitrified at 2PN stage is higher
than fresh embryo transfer.
This study is only data analysis, no additional collection of samples. This study does not
involve vulnerable groups.
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