Infertility, Female Clinical Trial
Official title:
Hysteroscopic Tubal Occlusion With the Use of Iso Amyl-2-cyanoacrylate in Patients With Hydrosalpinx
The purpose of this study is to assess the effectiveness of hysteroscopic tubal application of Iso Amyl-2-cyanoacrylate in occluding uterine tubes of infertile women with hydrosalpinx, which would make it an easy approach for occluding tubes with hydrosalpinx prior to IVF.
The study will be conducted according to the guidelines on human experimentation of the 1975
Declaration of Helsinki. For all patients after taking signed informed consent ,
transcervical hysteroscopic cannulation of the proximal one centimeter of fallopian tubes
with hydrosalpinx, will be done using a 4 Fr, 42cm long, polyethylene ureteric catheter,
where 0.5 ml of Iso Amyl-2-cyanoacrylate (AMCRYLATE®) will be injected.
All the surgical procedures will be performed without anesthesia, only premedication with an
NSAID (e.g. NaproxenR) is given orally one hour before the procedure.
Each patient will be under close observation for the first 24 hours postprocedure for any
signs of inflammation as abdominal pain, tenderness or fever and for the vital data.
Hysterosalpingography will be done for all patients 0ne and 3 months postinjection to confirm
tubal occlusion prior to IVF.
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