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Infertility, Female clinical trials

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NCT ID: NCT05585242 Recruiting - Infertility, Female Clinical Trials

Acceptance and Commitment Therapy (ACT) Adapted for Women With Infertility-related Distress

Start date: March 13, 2023
Phase: N/A
Study type: Interventional

This RCT will test the effect of a 7-week self-help ACT-based program in improving fertility-related quality of life and psychological flexibility, in women with infertility.

NCT ID: NCT05577806 Completed - Infertility, Female Clinical Trials

DYG Versus Cetrorelix in Oocyte Donation

Start date: January 1, 2017
Phase:
Study type: Observational

Prospective controlled study to assess the reproductive outcomes of OD recipients in which the donors were subjected to the DYG protocol (20mg/day) compared with those subjected to the short protocol with cetrorelix (0.25 mg/day) from Day 7 or since a leading follicle reached 14 mm. The OD cycles were triggered with triptoreline acetate and the trigger criterion was ≥3 follicles of diameter >18mm.

NCT ID: NCT05577455 Not yet recruiting - Infertility, Female Clinical Trials

Efficacy of Traditional Chinese Medicine on Ameliorating IVF-ET Outcomes of Diminished Ovarian Reserve Patients

Start date: November 10, 2022
Phase: Phase 3
Study type: Interventional

Patients with diminished ovarian reserve (DOR) who undergo in vitro fertilization and embryo transfer (IVF-ET) are included as the research subjects. The effects of Traditional Chinese Medicine (TCM) for kidney tonifying and blood circulation regulating of different intervention courses on ovarian hyporesponsiveness, IVF-ET outcome and clinical compliance in DOR patients are studied by a non-inferiority randomized controlled trial. The purpose is to identify the breakthrough point and treatment timing of TCM treatment, explore the best treatment course of TCM, and optimize the TCM therapeutic regimen.

NCT ID: NCT05528835 Completed - Female Infertility Clinical Trials

Caesarean Section and Intracytoplasmic Sperm Injection (ICSI) Outcome

Start date: January 1, 2022
Phase:
Study type: Observational [Patient Registry]

Although Caesarean section (CS) is often a necessary surgical intervention, it may also be associated with an increased risk of short- and long-term sequelae. It was thought that CS may increase the risk of female subfertility or even infertility. In assisted reproductive technology (ART) cycles, the process of implantation is believed to be the most important factor in determining pregnancy outcome. In view of conflicting results on the influence of a previous CS on outcomes of ART, this study will be conducted to investigate the impact of the mode of previous delivery on ICSI outcomes.

NCT ID: NCT05518175 Recruiting - Sterility, Female Clinical Trials

Patient-centered Outcomes After Permanent Female Sterilization Procedure(POPS Trial)

POPS
Start date: November 15, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to compare and capture key elements of the patient experience, quality of recovery, preferences and satisfaction after laparoscopic salpingectomy done via 3 different routes.

NCT ID: NCT05505474 Recruiting - Infertility, Female Clinical Trials

Use of a Subcutaneous Catheter for Controlled Ovarian Stimulation

Start date: November 2, 2023
Phase:
Study type: Observational

Subcutaneous medications are an integral part of controlled ovarian stimulation protocols for in-vitro fertilization (IVF), but daily or twice daily injections are both physically and emotionally burdensome for patients and their partners. This is a feasibility study to evaluate the use of the Neria Guard™ (Unomedical, Convatec) subcutaneous catheter for ovarian stimulation in IVF.

NCT ID: NCT05498350 Recruiting - Infertility, Female Clinical Trials

Randomized Trial Comparing Early "Trigger" Versus Delayed "Trigger" Timing in Cycles of Controlled Ovarian Stimulation.

Start date: August 10, 2022
Phase: N/A
Study type: Interventional

This randomized trial will compare the efficacy of two different times of administration of medications for final oocyte maturation, commonly called a "trigger", in cycles of controlled ovarian stimulation (COS) for cycles in which all embryos will be cryopreserved ("freeze-all cycles").

NCT ID: NCT05495711 Recruiting - Infertility, Female Clinical Trials

hUC Mesenchymal Stem Cells (19#iSCLife®-UT) Therapy for Patients With Thin Endometrial Infertility

Start date: August 1, 2022
Phase: Phase 1
Study type: Interventional

To explore the therapeutic effect and safety of human umbilical cord mesenchymal stem cells on thin endometrial infertility and to explore whether human umbilical cord mesenchymal stem cells using collagen as the carrier can promote endometrial growth, reduce the recurrence rate of intrauterine adhesion, increase the clinical pregnancy rate, improve the pregnancy outcome, and study its safety.

NCT ID: NCT05473273 Recruiting - Infertility, Female Clinical Trials

Descriptive Analysis of Serum Immunological Markers During an Euploid Frozen Embryo Transfer in a Natural Cycle.

Start date: April 24, 2023
Phase:
Study type: Observational

To describe the peripheral serum levels of the anti-inflammatory cytokines IL-4 (Interleukin-4), IL-10 (Interleukin-10), TGF-ß1 (Transforming Growth Factor beta1), the pro-inflammatory cytokines IL-17 (Interleukin-17), IFγ (Interferon Gamma) and the immune mediator PIBF (Progesterone-Induced Blocking Factor) along a single frozen euploid blastocyst transfer in a natural cycle (NC) or Hormone Replacement Therapy (HRT).

NCT ID: NCT05460858 Recruiting - Female Infertility Clinical Trials

NAC Effect on Infertile Women With Endometrioma

Start date: April 13, 2021
Phase: Phase 3
Study type: Interventional

Oxidative stress has been investigated as a key factor in the pathogenesis and progression of endometrioma. High follicular fluid ROS levels and serum can be related to negative IVF/ICSI outcomes in infertile women with endometrioma. Therefore, the use of antioxidants such as N-acetyl cysteine (NAC) may be reduced complications of endometrioma. To study this hypothesis, we designed a double-blind, randomized clinical trial study that aimed to determine the effect of N-acetyl cysteine (NAC) on stress oxidative factors and pregnancy outcomes in IVF/ICSI cycles in endometrioma patients.