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Infertility, Female clinical trials

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NCT ID: NCT03966339 Recruiting - Infertility,Female Clinical Trials

Growth Hormone Adding to Controlled Ovarian Hyperstimulation for Improving Embryo Quality

Start date: August 1, 2019
Phase: N/A
Study type: Interventional

GH plays an important role in the synthesis of ovarian steroid hormone and follicular development as a paracrine hormone.GH can regulate the growth hormone receptor and strengthen the function of mitochondria to improve the quality of the female oocyte.In this study, a prospective randomized control was used to explore the effect of GH adjuvant therapy on embryo quality.

NCT ID: NCT03965585 Completed - Infertility, Female Clinical Trials

Office Hysteroscopy in Infertility Work-out: the Role of Endometrial Hyperplasia in Southern Italian Women

Start date: January 2, 2019
Phase:
Study type: Observational

To assess the prevalence of endometrial hyperplasia (EH), endometrial intraepithelial neoplasia (EIN) and endometrial carcinoma between obese and not obese women undergoing IVF techniques for primary or secondary infertility.

NCT ID: NCT03964779 Not yet recruiting - Infertility, Female Clinical Trials

Prevalence of Thyroid Dysfunction and Anti-thyroid Antibodies in Infertile Women

Start date: May 2019
Phase:
Study type: Observational

The study population will be divided into three groups: - Group (A) consisting of 40 infertile women with either unexplained or anovulatory infertility with/without associated male factor of infertility, - Group (B) consisting of 40 infertile women with tubal (mechanical) factor of infertility with/without associated male factor of infertility, and - Group (C) consisting of 40 women with exclusive male factor of infertility and will be used as a control group. . All women will be subjected to: - Informed consent - Full history taking, including age, duration of infertility and whether primary or secondary - General and pelvix examination - Trans-vaginal ultrasonography - Determination of hormonal profile (FSH, LH, Estradiol, Prolactin) - Determination of ovulatory status - Determination of of tubal patency - Determination of presence of male factor - Determination of TSH and antithyroid antibodies (antithyroglobulin and antithyroid peroxidase) blood levels

NCT ID: NCT03954587 Terminated - Infertility Clinical Trials

What is the Optimal Cycle Regimen for Frozen- Thawed Embryo Transfer Cycles

Start date: June 10, 2019
Phase:
Study type: Observational

Investigators will be comparing artificial (HRT) frozen-thawed embryo transfer cycles to correctly conducted spontaneous natural cycles after the transfer of a chromosomally normal embryo.

NCT ID: NCT03951194 Recruiting - Infertility, Female Clinical Trials

Autologous Platelet Rich Plasma (PRP) Intra Ovarian Infusion in Perimenopausal Women

PRP
Start date: June 13, 2019
Phase: Phase 2/Phase 3
Study type: Interventional

Autologous PRP intra ovarian infusion may improve ovarian response and women's hormonal profile and may promote folliculogenesis in perimenopausal women.

NCT ID: NCT03946813 Completed - Infertility, Female Clinical Trials

The Efficacy of Platelets Rich Plasma for Ovarian Rejuvenation

Start date: August 20, 2018
Phase: N/A
Study type: Interventional

In recent years, an increased approach has appeared in the use of autologous blood products to assist tissue and organ healing. Application of platelet rich plasma (PRP) has emerged as a potential solution for infertile women with poor ovarian reserve in reproductive specialty.

NCT ID: NCT03937661 Recruiting - Infertility, Female Clinical Trials

Autologous Platelet-Rich Plasma Intra-ovarian Infusion in Poor Responders

PRP
Start date: May 6, 2019
Phase: Phase 2/Phase 3
Study type: Interventional

Autologous PRP intra ovarian infusion may improve ovarian response, patients' hormonal profile as well as fresh embryo transfer (ET)-ICSI cycles' outcome in patients presenting with Poor Ovarian Response (POR).

NCT ID: NCT03921710 Completed - Infertility, Female Clinical Trials

CAPA-IVM Versus STANDARD IVM

Start date: April 29, 2017
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate the effectiveness and safety of CAPA-IVM versus standard IVM in women with polycystic ovarian morphology (PCOM) or polycystic ovary syndrome (PCOS) .

NCT ID: NCT03916978 Recruiting - Menopause Clinical Trials

Autologous PRP Intra Ovarian Infusion to Restore Ovarian Function in Menopausal Women

PRP
Start date: May 21, 2019
Phase: Phase 2/Phase 3
Study type: Interventional

Autologous PRP intra ovarian infusion may restore ovarian function, may promote folliculogenesis and may improve hormonal profile of women in menopause.

NCT ID: NCT03910582 Not yet recruiting - Infertility, Female Clinical Trials

Personalized FET in RIF Patients With Displaced Dating

Start date: September 15, 2020
Phase: N/A
Study type: Interventional

The endometrium becomes receptive as a result of a series of timed hormonal events during the menstrual cycle. The exposure of the endometrium to progesterone after ovulation initiates morphological and functional alterations that result in the change from a pre-receptive to a receptive endometrium. The morphological changes observed on histology for each specific day after ovulation were described by Noyes and his colleagues in 1950. An endometrial biopsy that shows a difference of more than 2 days between the histologic dating and actual day after ovulation is considered to be "out of phase" However, the clinical application of the Noyes criterion is relatively limited. We have verified the Noyes criterion in natural cycle in previous study which conducting endometrial biopsies respectively on day 3, 5, 7, 9 and 11 of post-ovulation (PO+3/5/7/9/11)(unpublished data). The clinical value of the endometrial histological dating in RIF patients in natural cycle is still to be answered. In this study, we tried to investigate the clinical effects of pFET in unexplained RIF patients according to the use of classic histologic endometrial dating to estimate the timing of the window of implantation and to adjust embryo transfer time in natural cycle.