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Infertility, Female clinical trials

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NCT ID: NCT04616417 Completed - Infertility, Female Clinical Trials

Investigational Oocyte Cryopreservation for Medical and Non Medical Indications

Start date: May 8, 2015
Phase: N/A
Study type: Interventional

This is a prospective study to assess the long term benefits and outcomes of the existing oocyte cryopreservation methods for fertility preservation in women with a potential medical or non medical risk of loss of fertility

NCT ID: NCT04612959 Completed - Infertility, Female Clinical Trials

Effect of Psychosexual Caring Program on Sexual Well-being of Infertile Women

Start date: June 11, 2020
Phase: N/A
Study type: Interventional

The present study aims to examine the effect of the psychosexual caring program on the sexual well-being of infertile women.

NCT ID: NCT04610710 Recruiting - Infertility, Female Clinical Trials

Impact of Operation on Fertility for Women With Severe Endometriosis

EFFORT
Start date: August 1, 2020
Phase: N/A
Study type: Interventional

The EFFORT study compares the impact on fertility of operation or fertility treatment (IVF, in vitro fertilization) in a multicenter randomized controlled trial. The study population consists of women with colorectal deep infiltrating endometriosis and a pregnancy intention. These women will be randomized to either of the two treatment groups: Group A = Operation or Group B = fertility treatment (IVF). Group A will be further divided postoperatively into spontaneous conception or IVF depending on the Endometriosis Fertility Index score.

NCT ID: NCT04605107 Completed - Infertility, Female Clinical Trials

Biosimilarity Study of IM Injection of Human Chorionic Gonadotrophin After Parenteral Administration of Treatment A TEST Product Epifasi 5000 I.U. Ampoules (EIPICO PHARMA, EGYPT) and Treatment B REFERENCE Product Pregnyl 5000 I.U. Ampoules (Baxter Pharmaceutical Solutions for Organon, USA).

Start date: August 30, 2013
Phase: Phase 4
Study type: Interventional

Comparative randomized, single dose, parallel, triple-blinded study in infertile females to evaluate biosimilarity of IM Injection of Human Chorionic Gonadotrophin (HCG) after Parenteral administration of Treatment A TEST Product Epifasi 5000 I.U. Ampoules (EIPICO PHARMA, EGYPT) and Treatment B REFERENCE Product Pregnyl 5000 I.U. Ampoules (Baxter Pharmaceutical Solutions for Organon, USA)

NCT ID: NCT04554654 Recruiting - Infertility, Female Clinical Trials

Progesterone Levels and Endometrial Compaction in Frozen-Thawed Embryo Transfer Cycles

Start date: June 15, 2020
Phase:
Study type: Observational [Patient Registry]

This study is intended to determine whether there is a correlation between endometrial compaction and serum progesterone levels on the day of frozen embryo transfers by using transvaginal sonography for the endometrial assessment.

NCT ID: NCT04545918 Recruiting - Infertility, Female Clinical Trials

Convolutional Neural Network in Ovarian Follicle Identification

Start date: February 1, 2021
Phase:
Study type: Observational

A prospective cohort trial studying patients with infertility undergoing an ovarian stimulation with exogenous gonadotropins. Ovarian monitoring will be performed with a combination of transvaginal ultrasound and 2 dimensional human measurements of the follicle development on the right and left ovaries along with SonoAVC. Human and SonoAVC measurements will then be compared to mask region-based convolutional neural network in follicle identification and measurement during during the ovarian stimulation.

NCT ID: NCT04537078 Completed - Infertility, Female Clinical Trials

Progestin Primed Double Stimulation Protocol Versus Flexible GnRH Antagonist Protocol in Poor Responders

Start date: September 1, 2020
Phase: Phase 3
Study type: Interventional

The worldwide prevalence of primary and secondary infertility is estimated at ~2% and 10.5%, respectively, among women aged 20-44 years and attempting to conceive. Poor ovarian responders (PORs) involve 9-24% of patients undergoing in-vitro fertilization (IVF). proper tailoring of the ovarian stimulation protocol in order to maximize the number of oocytes collected represents a crucial step for them to eventually conceive. Recent evidence indicates that in the same menstrual cycle, there are multiple follicular recruitment waves. This coincides with the theory that folliculogenesis occurs in a wave-like fashion. Thus, within a single menstrual cycle, there can theoretically be multiple opportunities for a clinician to collect oocytes, as opposed to the conventional single cohort of antral follicles during the follicular phase. Utilizing this concept, clinicians have been attempting to retrieve oocytes from poor responders using both the follicular-phase stimulation (FPS) and the luteal-phase stimulation (LPS) protocols to increase the number of oocytes collected shorter within shorter period of time. By increasing the number of the retrieved oocytes collected, a better clinical can be assured since there is a clear relationship between the number of oocytes collected and live birth rates across all female age groups. which protocol is the most effective remains controversial and the efficacy of PPOS in POR compared with that of conventional protocols is unclear.

NCT ID: NCT04528849 Recruiting - Clinical trials for Polycystic Ovary Syndrome

Comparison of Ovulation Induction Cycle Outcomes Between Early and Late Dose Increments for Low Dose Gonadotropin Step-up Protocol Among Infertile Women Diagnosed With Polycystic Ovary Syndrome: Prospective Randomised Trial

Start date: August 20, 2020
Phase: N/A
Study type: Interventional

Low dose gonadotropin step-up ovulation induction treatment is the universally accepted and utilized teratment protocol for infertile women diagnosed with polycystic ovary syndrome (PCOS). First dose increment is advised on 14th day of ovarian stimulation with gonadotropins to decrease multiple follicle generation and cycle cancellation rates. However, clinicians impatiently increase gonadotropin dose on 7th day of stimulation without strong scientific evidence. This randomised controlled study will be the first study which will compare safety and ovulation induction cyle outcomes of early and late dose increments among infertile women diagnosed with PCOS.

NCT ID: NCT04528277 Not yet recruiting - Infertility, Female Clinical Trials

Short Course Rifapentine and Isoniazid for the Preventive Treatment for Latent Genital Tuberculosis

SCRIPT-LGTB
Start date: September 1, 2020
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess the efficacy, safety and tolerability of the 1-month regimen of three times weekly rifapentine plus isoniazid in improving fertility outcome in recurrent implantation failure (RIF) patients with latent genital tuberculosis (LGTB), compared to no treatment and non-LGTB patients.

NCT ID: NCT04518202 Not yet recruiting - Infertility, Female Clinical Trials

Transdermal Lidocaine for Pain Control During Diagnostic Office Hysteroscopy

Start date: September 1, 2020
Phase: N/A
Study type: Interventional

To compare the effectiveness of Transdermal Lidocaine for Pain Control During Diagnostic Office Hysteroscopy