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Infertility, Female clinical trials

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NCT ID: NCT03843112 Completed - Infertility, Female Clinical Trials

Modulating the Vaginal Microbiome After Implantation Failure

Start date: March 1, 2019
Phase: Phase 4
Study type: Interventional

Vaginal microbiome has in studies shown a link with the outcome of fertility treatment. The investigators wish to determine if it is possible to change an unfavorable vaginal microbiome using lactobacilli loaded vaginal supplements.

NCT ID: NCT03809429 Completed - Infertility, Female Clinical Trials

Follitropin Delta in Long GnRH Agonist and GnRH Antagonist Protocols (BEYOND)

BEYOND
Start date: April 29, 2019
Phase: Phase 3
Study type: Interventional

To compare the efficacy and safety of FE 999049 (follitropin delta) and its personalized dosing algorithm in controlled ovarian stimulation for in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) using a long gonadotropin-releasing hormone (GnRH) agonist protocol versus a short GnRH antagonist protocol.

NCT ID: NCT03802032 Completed - Infertility, Female Clinical Trials

Topical Analgesia for Pain Relief in Hysterosalpingography

HSG
Start date: February 1, 2019
Phase: N/A
Study type: Interventional

The study will involve giving topical analgesia or placebo and then assessing pain and satisfaction during and after the procedure in order to see wed to the placebo.hether the topical analgesia has helped in decreasing pain associated with the procedure and also whether it has increasedd satisfaction with the procedure compar

NCT ID: NCT03788421 Completed - Sterility, Female Clinical Trials

Comparison Between 2 Techniques for Bilateral Salpingectomy

Start date: January 1, 2019
Phase: N/A
Study type: Interventional

A comparison between 2 techniques for bilateral salpingectomy during cesarean section. Primary outcomes are total operative time and bilateral completion of the randomized procedure. Secondary outcomes included surgical complications and post operation complications.

NCT ID: NCT03770026 Completed - Clinical trials for Infertility, Female, Associated With Anovulation

Autologous Platelet-rich Plasma for Clomiphene Citrate-induced Thin Endometrium

Start date: January 1, 2018
Phase: Phase 2/Phase 3
Study type: Interventional

This is a prospective self-controlled clinical study. Women with clomiphene Citrate failure with thin endometrium less than 7 millimeters for at least 3 cycles will be selected (N = 30). Patients will receive 2 ovarian stimulation cycles with Clomiphene citrate (CC) 100 mg/ day for 5 days from cycle day 3. A control cycle (CC only cycle) woman will continue on CC alone plus cervical irrigation of cervix with 1 ml of 0.9% normal saline at cycle day 8 and 10 to assure patient-blinded method. The study group, the same will be done plus the intrauterine infusion of Autologous platelet-rich plasma (PRP) in 8th and 10th days of the cycle. In both groups, the endometrial thickness and Power Doppler evaluation of their endometrial and sub-endometrial blood flow will be measured on the day of Human Chorionic Gonadotropin (HCG) administration.

NCT ID: NCT03767218 Completed - Infertility, Female Clinical Trials

Initiation of Ovarian Stimulation With Recombinant-human FSH (Bemfola®) in the Late Follicular Phase

Start date: November 1, 2018
Phase: Phase 3
Study type: Interventional

A randomised controlled open-label clinical trial to compare the outcome parameters after ovarian stimulation using recombinant-human FSH (follicle stimulating hormone), starting on day 2 of the cycle versus start in the late follicular phase of the cycle.

NCT ID: NCT03759301 Completed - Infertility, Female Clinical Trials

Efficacy of Growth Hormone Supplementation With Gonadotrophins in IVF/ICSI for Poor Responders

Start date: December 20, 2018
Phase: Phase 4
Study type: Interventional

The objective of this study is to assess the effectiveness of adjuvant growth hormone injection during controlled ovarian stimulation, in poor responder women undergoing intracytoplasmic sperm injection (ICSI) procedures.

NCT ID: NCT03755973 Completed - Infertility, Female Clinical Trials

Effect of Different Ovarian Stimulation Protocols on Endometrial Receptivity

Start date: January 29, 2020
Phase: Phase 4
Study type: Interventional

This study will assess the change in endometrial gene expression signature on the day of embryo transfer according to the type of exogenous gonadotropins administered.

NCT ID: NCT03755037 Completed - Female Infertility Clinical Trials

Clomiphene Citrate, Estradiol and Sildenafil for Induction of Ovulation in Unexplained Infertility

Start date: January 31, 2017
Phase: Phase 1
Study type: Interventional

Diagnosis of unexplained infertility is made after the recommended testing fails to reveal any abnormality. The treatment for unexplained infertility is empiric because it does not address a specific defect or functional impairment. The principal treatments for unexplained infertility include expectant observation with timed intercourse and lifestyle changes, clomiphene citrate and intrauterine insemination (IUI), controlled ovarian hyperstimulation (COH) with IUI, and IVF).

NCT ID: NCT03747692 Completed - Infertility, Female Clinical Trials

Intracervical Anasthesia in Outpatient Hystroscopy, Can Procedure be Completed Diagnostic and Therapeutic With no Need to General Anaesthesia

Start date: August 15, 2018
Phase: N/A
Study type: Interventional

Single blind randomized controlled study in which 80 patients coming for hystroscopy due to multiple indication as infertility, AUB and missed IUD were assigned for our study. Both Sample size and randomization were done by a computer program. Patients were classified into 2 groups, group 1 study group was subjected to intracervical injection of 5 mi of mepivacaine hydrochloride at position 3 and 9 of the vaginal portion of the cervix, and at least 5 minutes post injection before procedure done. The control group received NSAI injection 15 minutes before procedure and 5 ml of saline was injected in each side of cervix at 3 9 positions. Hystroscopy was done if an abnormality is detected an intervention was done. A descriptive scale of pain was done into mild, moderate or severe (that lead to interruption of the procedures).