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NCT04552210 Clinical Trial

Mannose Binding Lectin Gene Polymorphism Versus Microbial Virulence in the Pathogenesis of Vulvovaginal Candidiasis

Infection Clinical Trial

Official title:
Mannose Binding Lectin Gene Polymorphism Versus Microbial Virulence in the Pathogenesis of Vulvovaginal Candidiasis in Egypt

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT04552210
Other study ID # Mannose
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date September 16, 2020
Est. completion date February 20, 2021

Study information
Verified date November 2020
Source Aljazeera Hospital
Contact Mahmoud Alalfy
Phone 01002611058
Email mahmoudalalfy@ymail.com
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The vaginal mucosa is inhabited by both fungal and bacterial microorganisms which normally co-exist with the host in a tightly regulated and commensal manner.

Description:

Nevertheless, under certain circumstances, this co-existence can turn into a pathologic state followed by symptomatic disease

Recruitment information / eligibility
Status Recruiting
Enrollment 50
Est. completion date February 20, 2021
Est. primary completion date December 15, 2020
Accepts healthy volunteers
Gender Female
Age group 18 Years to 42 Years
Eligibility Inclusion Criteria: - 1. Married females in the reproductive age period. 2. Females complaining of vaginal discharge (whitish and scanty), itching, dyspareunia, pruritis, and signs of vulvovaginitis ie. erythema. Exclusion Criteria: - females who attended the same clinic in the same period, matched the cases regarding the age group, without having Candida infection as confirmed by culture of vaginal swabs.

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• blood sample
Whole blood was collected on EDTA (1mg/ml) to prevent clotting and DNA degradation.

Locations
Country Name City State
Egypt Algazeerah Giza

Sponsors (2)
Lead Sponsor Collaborator
Aljazeera Hospital Cairo University

Country where clinical trial is conducted

Egypt, 

Outcome
Type Measure Description Time frame Safety issue
Primary the number of women who have mutation in MBL2 gene polymorphism women who have mutation in MBL2 gene polymorphism a month
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