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Clinical Trial Summary

This is a Phase 2, randomized, double-blind, placebo-controlled study comparing the efficacy and safety of avapritinib + best supportive care (BSC) with placebo + BSC in patients with indolent systemic mastocytosis (ISM) whose symptoms are not adequately controlled by BSC. The study will be conducted in 3 parts. All patients will receive treatment with avapritinib during Part 3 including those rolling over from the placebo group.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03731260
Study type Interventional
Source Blueprint Medicines Corporation
Contact
Status Active, not recruiting
Phase Phase 2
Start date April 16, 2019
Completion date January 31, 2028

See also
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