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NCT06366581 Clinical Trial

Transcriptomic Analysis of Incisional Hernia Based on High-throughput Sequencing Technology

Incisional Hernia Clinical Trial

Official title:
Transcriptomic Analysis of Incisional Hernia Based on High-throughput Sequencing Technology

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT06366581
Other study ID # HD20240307
Secondary ID
Status Completed
Phase
First received
Last updated
Start date March 1, 2023
Est. completion date March 1, 2024

Study information
Verified date March 2024
Source Fudan University
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

This study included patients who underwent surgical treatment for incisional hernia and non-hernia conditions. Surgical specimens were collected for transcriptome sequencing to obtain the gene expression list. Then genes analyzed by Gene Ontology, protein interactions, and signaling pathway enrichment using the expression matrix.

Recruitment information / eligibility
Status Completed
Enrollment 36
Est. completion date March 1, 2024
Est. primary completion date September 1, 2023
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 75 Years
Eligibility Inclusion Criteria: 1.18 to 75 years 2.diagnosed with incisional hernia 3.normal tumour markers 4.elective surgery patients. Exclusion Criteria: 1. patients with vital organ failure (heart liver, lung, kidney and others) 2. malignant tumors not been completely relieved by active treatment, 3. patients who have psychiatric diseases or comprehension disorders. 4. patients with metabolic disease involving connective tissue collagen.

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• Transcriptomic analysis
high-throughput sequencing technology

Locations
Country Name City State
China Hua Dong Hospital Affiliated to Fu Dan University Shanghai

Sponsors (1)
Lead Sponsor Collaborator
Fudan University

Country where clinical trial is conducted

China, 

Outcome
Type Measure Description Time frame Safety issue
Primary the gene expression list the gene expression list 2023.3-2023.9
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