Secondary Intention Wound Healing Versus Micrografting in Patients Undergoing Mohs Surgery — MomelanMohs  

Impaired Wound Healing Clinical Trial

Official title: Secondary Intention Wound Healing Versus Micrografting in Patients Undergoing Mohs Surgery

Status Terminated

Clinical Trial Summary

This study evaluates a novel micrografting technique to see how it will influence the healing rate and cosmetic result of second intention wounds. The graft harvesting and micrografting process was designed by MoMelan Technologies The Epidermal Expansion System, which is composed of a commercially available Blister Generation Device and the Microblister Generation and Excision Device (MBGED), will generate an array of small microblisters and transfer the micrografts to a sterile dressing (Tegaderm™ - an FDA approved wound dressing) for application to the subject's surgical area. The investigators predict that applying expanded micrografts to wounds that otherwise would have healed by second intention alone will hasten healing and possible reduce scarring.

Clinical Trial Description

Participants with a scalp wound s/p Mohs procedure will be randomized to a micrografting technique intervention or to no intervention/heal with secondary intention alone (control). Intervention consists of harvesting skin micrografts (1.75mm) from pigmented skin using the Microblister generation and excision device and transfer the micrografts to a sterile dressing for application to the participants scalp wound. Percent wound re-epithelialization will be compared between two groups. ;

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Impaired Wound Healing

• NCT number: NCT01442844
• Study type: Interventional
• Source: Massachusetts General Hospital
• Status: Terminated
• Phase: N/A
• Start date: September 2011
• Completion date: May 2013