Impacted Third Molar Tooth Clinical Trial
— AITSOfficial title:
Examination of the Prevention and Treatment Modalities of Alveolitis in Relation With Impacted Teeth Surgery
Verified date | November 2018 |
Source | University of Pecs |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
In the everyday clinical practice the incidence of minor complications is approximately 15-20% of the total number of third molar removals. Alveolitis (dry socket syndrome) may arise in 30-40% of the surgical tooth removals. Several preventive approaches are known, such as the use of iodoform gauze, zink-oxide eugenol paste, platelet rich fibrin (PRF), different medicine containing pastes, like antibiotics containing, non-steroid pain killer containing, steroid containing, or the application of chlorhexidine gel and solutions. In the case of a manifest alveolitis these methods can be used as well. The aims of this research are: i) to identify the important pathogens which play role in the development of alveolitis (microbiological methods), ii) to analyze the in vitro effectivity of the different antiseptic materials in case of infections (inhibitory zones) iii) to compare the effectivity of different alveolitis preventive methods in a prospective clinical study, iv) to compare the different treatment options in alveolitis in a prospective clinical study.
Status | Recruiting |
Enrollment | 50 |
Est. completion date | September 30, 2021 |
Est. primary completion date | September 30, 2020 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 100 Years |
Eligibility |
Inclusion Criteria: - Pell-Gregory II/B impaction - mesioangular impactions - tooth sectioning is not necessary for removal - without local infection of third molar Exclusion Criteria: - no general diseases or following treatments (DM, steroids, bleeding risk, chemotherapy, radiotherapy, bisphosphonates, immunosuppressive conditions) |
Country | Name | City | State |
---|---|---|---|
Hungary | Department of Oral and Maxillofacial Surgery, University of Pécs | Pécs |
Lead Sponsor | Collaborator |
---|---|
University of Pecs |
Hungary,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Change in minor postoperative complications (trismus) | Measuring postoperative trismus (maximal mouth opening - inter-incisal distance in millimeters). | day of surgery, 3rd, 7th postoperative days | |
Primary | Change in minor postoperative complications (oedema) | measuring postoperative oedema (flexible ruler- lateral canthus-mandibular angle distance in millimeters and tragus-labial commissure distance in millimeters). | day of surgery, 3rd, 7th postoperative days | |
Primary | Change in minor postoperative complications (pain) | Measuring level of pain in Visual Analog Scale (minimum score is 0 which represents no pain, maximum score is 10 which shows the worst pain) postoperatively | 1st, 2nd, 3rd, 4th, 5th, 6th and 7th postoperative days | |
Primary | Change in necessity of postoperatively taken analgesics | Registering dose of active agent of taken analgesics in milligrams . | 1st, 2nd, 3rd, 4th, 5th, 6th and 7th postoperative days | |
Primary | Change in necessity of postoperatively taken analgesics | Registering number of daily repeats of taken analgesics. | 1st, 2nd, 3rd, 4th, 5th, 6th and 7th postoperative days |
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