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Clinical Trial Summary

The concept of immediate implant placement at the time of tooth extraction was first introduced by Schulte et al. on animal studies. Since then, many follow‑up studies examining different variables have supported the concept of immediate implant placement. pioneered a major contribution to immediate implant placement in human studies which recommended the insertion of an implant into a fresh extraction socket.

They advocated immediate implant placement primarily to reduce the number of surgical interventions needed to perform an implant‑supported rehabilitation and shorten the treatment time.

Placement of implants immediately into extraction sites allow the surgeon to idealize the position of the implant appropriately with a better rehabilitation of the normal contour to the facial aspect of the final restoration.

Immediate implant placement in fresh extraction sockets was reported to reduce alveolar bone resorption. Better esthetic outcomes were achieved including the prosthetic crown length in harmony with the adjacent teeth, natural scalloping and easier distinct papillae to achieve and maximum soft tissue support.

Hyaluronic acid is a glycosaminoglycan, this unique molecule is implicated In a variety of biological functions including structural integrity, and the regulation of embryologic development. It is described as a natural organic substance, with physiological therapy activity, main component of the extracellular matrix of many tissues such as the skin, synovial joints and periodontal tissues .


Clinical Trial Description

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Study Design


Related Conditions & MeSH terms


NCT number NCT03804177
Study type Interventional
Source Cairo University
Contact ahmed Nasser, Msc
Phone 00201094959526
Email ahmedelsawi8787@gmail.com
Status Not yet recruiting
Phase Phase 4
Start date February 10, 2019
Completion date April 30, 2022

See also
  Status Clinical Trial Phase
Completed NCT03691467 - the Effect of Topical Application of Hyaluronic Acid on Immediate Dental Implant Phase 4
Completed NCT03689998 - Evaluation of Melatonin Application of Immediate Dental Implant Phase 4
Not yet recruiting NCT04449302 - Evaluation of Papilla Index Around Immediate Mandibular Molar Implants Using Customized Healing Abutment Versus Submerged Healing N/A
Not yet recruiting NCT03692026 - Assessment of Immediate Implant Stability When Adding Mixture of Hyaluronic Acid and Melatonin Phase 4
Completed NCT02864862 - Esthetic Outcomes Following Immediate Implant Combine With Soft Tissue Augmentation Phase 4
Completed NCT04343833 - Immediate Implants in the Aesthetic Zone N/A
Recruiting NCT06455436 - Dimensional Changes of Peri-implant Tissue in Immediate Implants With Individualized Healing Abutments N/A
Active, not recruiting NCT03183349 - Immediate Implant Placement With Platlet Rich Fibrin as Space Filling Material Versus the Use of Deprotienized Bovine Bone (Tutogen) in Maxillary Premolars. N/A
Completed NCT05101941 - Immediate Dental Implant Placed in the Presence of Chronic Inflammatory Periapical Lesions N/A