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Precise Transplantation of Human Amniotic Epithelial Stem Cells Into Lateral Ventricle for Parkinson's Disease

Idiopathic Parkinson's Disease Clinical Trial

Official title:
Precise Transplantation of Human Amniotic Epithelial Stem Cells Into Lateral Ventricle for Parkinson's Disease

Clinical Trial Summary

This is a single-center, single-arm, dose escalation study, to explore the safety, tolerability and efficacy of human amniotic epithelial stem cells (hAESCs) for idiopathic Parkinson's disease (PD).

Clinical Trial Description

hAESCs will be administration through the Ommaya reservoir implanted into the lateral ventricle of subjects with idiopathic PD. This dose escalation will be followed by an exploratory expansion phase in 3 cohorts. - Dose A (5×10^7 cells/dose) - Dose B (1.0×10^8 cells/dose) - Dose C (1.5×10^8 cells/dose). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05691114
Study type Interventional
Source Shanghai East Hospital
Contact Jingwen Wu, M.D.
Phone 021-38804518
Email wujingwendongfang@163.com
Status Recruiting
Phase Phase 1
Start date February 2023
Completion date February 2026
View Details
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