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Hypotension clinical trials

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NCT ID: NCT00257504 Completed - Clinical trials for Intradialytic Hypotension

Central Blood Volume in Hypotensive Dialysis Patients

Start date: November 2005
Phase: N/A
Study type: Observational

The purpose of the study is to test whether hypotensive episodes during dialysis - caused by withdrawal of fluid drom the circulation - can be predicted by means of two harmless monitoring techniques.

NCT ID: NCT00256724 Completed - Hypotension Clinical Trials

Efficacy Study of a Facemask Device to Treat Hypotension

Start date: June 2005
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine if the impedance threshold device (ITD) attached to a facemask can increase blood pressure in patients who present to the emergency department with hypotension secondary to hypovolemia. The cause of hypovolemia could be blood loss, sepsis, or dehydration.

NCT ID: NCT00248807 Completed - Clinical trials for Spinal Cord Injuries

A Study of Blood Pressure and Blood Supply to the Brain in Persons With a Spinal Cord Injury.

Start date: October 2005
Phase: N/A
Study type: Interventional

The purpose of this study is to determine how blood pressure and blood flow are controlled during head-up tilt in a semi-upright position. In this investigation we are studying blood pressure and blood flow to the brain, with and without a medication which lowers blood pressure (Vasotec). We will determine how persons with a spinal cord injury are able to maintain blood flow to the brain (not get dizzy) as they assume a more upright position and their blood pressure decreases.

NCT ID: NCT00237770 Completed - Spinal Cord Injury Clinical Trials

Prevention of Low Blood Pressure in Persons With Tetraplegia

Start date: June 2003
Phase: Phase 2/Phase 3
Study type: Interventional

The aim of this investigation is to determine the blood pressure response to NOS inhibition, with L-NAME, in persons with tetraplegia compared to non-SCI control subjects and to establish if blood pressure can be increased while upright in those with tetraplegia. If blood pressure is increased with NOS inhibition in persons with tetraplegia, this would improve our treatment of the condition of low blood pressure during seated postures in individuals with tetraplegia.

NCT ID: NCT00231699 Completed - Child Clinical Trials

A Comparison of Prevention of Hypothermia in Pediatric Patient Between Wrapping With Cotton and Plastic.

Start date: January 2004
Phase: N/A
Study type: Interventional

Hypothermia leads to increased morbidity and mortality. Heat loss mainly occurs during anesthesia and surgery. Therefore prevention of hypothermia in pediatric patients undergoing general anesthesia is very important. However, there is very little information about effectiveness of various insulating materials used in the operating room. Objective: To compare the effectiveness of cotton and plastic for prevent intraoperative hypothermia in pediatric patients.

NCT ID: NCT00223691 Completed - Clinical trials for Orthostatic Hypotension

Treatment of Orthostatic Hypotension in Autonomic Failure

Start date: March 2002
Phase: Phase 1
Study type: Interventional

The autonomic nervous system serves multiple regulatory functions in the body, including the regulation of blood pressure and heart rate, gut motility, sweating and sexual function. There are several diseases characterized by abnormal function of the autonomic nervous system. Medications can also alter autonomic function. Impairment of the autonomic nervous system by diseases or drugs may lead to several symptoms, including blood pressure problems (e.g., high blood pressure lying down and low blood pressure on standing), sweating abnormalities, constipation or diarrhea and sexual dysfunction. Because treatment options for these patients are limited. We propose to study patients autonomic failure and low blood pressure upon standing and determine the cause of their disease by history and examination and their response to autonomic testing which have already been standardized in our laboratory. Based on their possible cause, we will tests different medications that may alleviate their symptoms.

NCT ID: NCT00190788 Completed - Sepsis Clinical Trials

Extended Therapy of Drotrecogin Alfa (Activated) 4 vs 7 Days Infusion

Start date: June 2004
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether continued administration of Drotrecogin Alfa (Activated) up to additional 72 hours - after the so far recommended 96 hour infusion period - results in a more rapid resolution of hypotension in severe septic patients.

NCT ID: NCT00135668 Completed - Hypotension Clinical Trials

Dose-response Study of Sodium Nitroprusside in Children Requiring Controlled Hypotension in the Operating Room

Start date: August 2005
Phase: Phase 2
Study type: Interventional

Sodium nitroprusside (SNP) has been approved for control of blood pressure in adults, yet there are no controlled studies in children. The purpose of this study is to determine the efficacy and safety of sodium nitroprusside in children who will be having surgery, and who require blood pressure lowering in order to decrease the amount of blood loss during their surgery.

NCT ID: NCT00117585 Completed - Clinical trials for Hypotension, Orthostatic

Orthostatic Hypotension in Rehabilitation Patients

Start date: November 2005
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the prevalence and clinical course of orthostatic hypotension (OH) on a rehabilitation and nursing home unit during their inpatient stay and to initiate a standardized, interdisciplinary treatment plan for patients with OH and determine the effect of treatment on the clinical course of OH during their inpatient stay.

NCT ID: NCT00115726 Completed - Hypertension Clinical Trials

Trial Assessing the Effect of Preoperative Furosemide on Intraoperative Blood Pressure

Start date: September 2000
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether continuing or discontinuing furosemide (a diuretic) on the day of elective noncardiac surgery for those who take furosemide on a chronic basis, causes more intraoperative hypotension (low blood pressure) during surgery. Our hypothesis is that the usual practice of continuing furosemide on the day of surgery would contribute to more hypotension during surgery than discontinuing furosemide.