Hypotension in Children With Down Syndrome With Anesthesia Induction

Status Completed

Clinical Trial Summary

Children generally undergo induction of anesthesia by inhalation of sevoflurane. Children with Down Syndrome experience bradycardia with induction of anesthesia using sevoflurane. It is unknown if this bradycardia is isolate or results in hypotension, thus requiring treatment. Isolate bradycardia without hypotension does not require treatment and should be avoided as many of these patients have underlying cardiac anomalies.

Clinical Trial Description

Children generally undergo induction of anesthesia by inhalation of sevoflurane. This is particularly relevant for children with developmental delays as to avoid placement of an IV while awake. However, children with Down Syndrome experience bradycardia with induction of anesthesia using sevoflurane. It is unknown if this bradycardia is isolate or results in hypotension, thus requiring treatment. Isolate bradycardia without hypotension does not require treatment and should be avoided as many of these patients have underlying cardiac anomalies. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04603469
Study type	Observational
Source	Baylor College of Medicine
Contact
Status	Completed
Phase
Start date	May 26, 2021
Completion date	October 28, 2021

View Details

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