Efficacy of KCl Plus 0.9%NaCl Compare With KCl Plus 0.45%NaCl

Status Recruiting

Clinical Trial Summary

evaluate efficacy and safety of IV administration of potassium chloride (KCl) plus 0.9%NaCl compare with KCl plus half-strength normal saline solution (0.45%NaCl) in correcting hypokalemia

Clinical Trial Description

Hypokalemia is frequently encountered in hospitalized patients. Intravenous (IV) potassium repletion with saline is preferred used for initial therapy. However, administration of normal saline (0.9%NaCl) usually provokes sodium and potassium diuresis, thus, it might delay reversal of the hypokalemia.

Object of this study : to evaluate efficacy and safety of IV administration of potassium chloride (KCl) plus 0.9%NaCl compare with KCl plus half-strength normal saline solution (0.45%NaCl) in correcting hypokalemia. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Hypokalemia

Clinical Trial Details

NCT number	NCT02721095
Study type	Interventional
Source	Phramongkutklao College of Medicine and Hospital
Contact	Theerasak Tangwonglert, MD.
Phone	0897750222
Email	theerasak.pmk@gmail.com
Status	Recruiting
Phase	Phase 4
Start date	August 2014
Completion date	September 2016

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT02926989` - Intravenous Fluids in Hospitalised Children	Phase 4
Completed	`NCT00718068` - Safety of Continuous Potassium Chloride Infusion in Critical Care	Phase 4
Recruiting	`NCT04428827` - Outcome of Patients With Primary Aldosteronism
Completed	`NCT05184998` - Description of the Clinical Outcomes of Hospitalized Patients With Heart Failure With Different Serum Potassium Levels
Completed	`NCT01431326` - Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care
Recruiting	`NCT04278404` - Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)
Completed	`NCT01572454` - Comparison of Dexmedetomidine and Remifentanil Infusion During CABG	N/A
Not yet recruiting	`NCT02709031` - Cicletanine in Hypertension With Diabetes: Added Magnesium Preserves Potassium and Sodium	Phase 1/Phase 2
Completed	`NCT04426994` - Hypomagnesemia Associated With Proton-Pump Inhibitor Use
Completed	`NCT05118022` - Artificial Intelligence Identified Dyskalemia Using Electrocardiogram (AIDE)	N/A
Terminated	`NCT02082717` - The Impact of Neut During Potassium Chloride Replacement on Pain and Incidence of Phlebitis	Phase 4
Completed	`NCT00605202` - Effect of Licorice and Hydrochlorothiazide on Plasma Potassium	Phase 4
Recruiting	`NCT03833089` - Targeted Potassium Levels for Prevention of ICD Therapy	Phase 4