Hypertrophy Clinical Trial
— HAMOfficial title:
Does Obtaining the Majority of Dietary Protein From Non-animal Sources Support the Skeletal Muscle Adaptive Response to Structured Resistance Training in Young Men and Women
Verified date | May 2021 |
Source | University of Exeter |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
Protein is vital for the preservation of health and optimal adaptation to training. However, animal proteins come with economic and environmental issues. The study will investigate the effect of non-animal vs animal based habitual protein consumption on muscle protein metabolism and changes in muscle mass and function over a longer period of time.
Status | Active, not recruiting |
Enrollment | 42 |
Est. completion date | May 1, 2022 |
Est. primary completion date | March 1, 2020 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 40 Years |
Eligibility | Inclusion Criteria: - Males and females 18 - 40 years of age. - Body mass index between 18 and 30. - Recreationally active. - Resistance training experienced (have previous performed resistance exercise, and are familiar with the basic movements). Exclusion Criteria: - Any diagnosed metabolic impairment (e.g. type 1 or 2 Diabetes) (as this may affect normal protein metabolism). - Any diagnosed cardiovascular disease or hypertension (to avoid any complications associated with heavy exercise). - Elevated blood pressure at the time of screening. (An average systolic blood pressure reading of =140mmHg over two or more measurements and an average diastolic blood pressure of =90mmHg over two or more measurements.) - Chronic use of any prescribed or over the counter pharmaceuticals (that may modulate muscle protein metabolism). - A personal or family history of epilepsy, seizures or schizophrenia. - Allergic to mycoprotein / Quorn, penicillin, or milk. - Pregnancy. |
Country | Name | City | State |
---|---|---|---|
United Kingdom | University of Exeter, Sports & Health Sciences, College of Life & Environmental Sciences | Exeter | Devon |
Lead Sponsor | Collaborator |
---|---|
University of Exeter | Quorn |
United Kingdom,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Muscle Protein Synthesis | Muscle protein synthesis measured via deuterium oxide | 3 days | |
Secondary | Muscle fiber CSA | Changes in muscle fiber CSA | 10 weeks | |
Secondary | Muscle Strength | Changes in muscle strength | 10 weeks | |
Secondary | Muscle CSA | Changes in muscle CSA as measured by MRI | 10 weeks |
Status | Clinical Trial | Phase | |
---|---|---|---|
Recruiting |
NCT05945641 -
Effect of Low-load Resistance Training vs. High-intensity Interval Training on Local Muscle Endurance
|
N/A | |
Not yet recruiting |
NCT05544955 -
Protein Ingestion Timing on Body Composition and Biochemical Markers in Resistance-trained Males
|
N/A | |
Completed |
NCT04411173 -
Effect of Daily Doses of Rice or Whey Protein on Resistance Training Adaptations
|
N/A | |
Completed |
NCT04381390 -
Egg Consumption and Muscular Adaptations
|
N/A | |
Completed |
NCT04535596 -
Blood Flow Restriction Exercises and Conservative Exercises in Knee Osteoarthritis
|
N/A | |
Completed |
NCT04213586 -
Effects of Whey Protein and Collagen Supplementation
|
N/A | |
Completed |
NCT03918395 -
Supplemental Protein And Resistance Training Adaptations
|
N/A | |
Completed |
NCT05058794 -
Comparison Among the Effects of Blood Flow Restriction Training and Conventional Exercise in Knee Osteoarthritis.
|
N/A | |
Recruiting |
NCT04750694 -
High Intensity Resistance Training Combined With Blood Flow Restricted Exercise in Elite Handball Players
|
N/A | |
Completed |
NCT06121869 -
Dileucine and Resistance Training Adaptations
|
N/A | |
Not yet recruiting |
NCT06075901 -
Reliability and Performance Analysis of the Use of Tissue Flossing for Blood Flow Restriction.
|
N/A | |
Recruiting |
NCT05774444 -
Investigating the Effects of Krill Oil and Krill Protein on Post-exercise Muscle Protein Metabolism
|
N/A | |
Recruiting |
NCT05576337 -
Neuromuscular Characteristics of Strict Vegetarians and Non-Vegetarians Women
|
N/A | |
Withdrawn |
NCT04256343 -
D2O Dosing Strategies to Assess Muscle Protein Synthesis
|
N/A | |
Completed |
NCT03870165 -
Food First Approach to Stimulate Muscle Protein Synthesis in Healthy Adults
|
N/A | |
Completed |
NCT04845295 -
Resistance Training Effects on Muscle Morphological, Mechanical and Contractile Properties
|
N/A | |
Recruiting |
NCT03565302 -
Beta2-adrenergic Agonism and Muscle Remodelling
|
N/A | |
Completed |
NCT03117127 -
Muscle Protein Synthesis After Whole Egg vs. Egg White Consumption
|
N/A | |
Not yet recruiting |
NCT06164249 -
Quantification of Internal Training Load
|
N/A | |
Completed |
NCT03723226 -
BFR and Muscle Mitochondrial Oxidative Capacity
|
N/A |